Radiation-induced lung injury

Last updated
Radiation-induced lung injury
Radiation pneumonitis (4863802675).jpg
Radiation pneumonitis
Specialty Pulmonology   OOjs UI icon edit-ltr-progressive.svg

Radiation-induced lung injury (RILI) is a general term for damage to the lungs as a result of exposure to ionizing radiation. [1] In general terms, such damage is divided into early inflammatory damage (radiation pneumonitis) and later complications of chronic scarring (radiation fibrosis). Pulmonary radiation injury is an unavoidable risk of radiation therapy administered to treat thoracic or lung cancer. [2]

Contents

Symptoms and signs

The lungs are a radiosensitive organ, and radiation pneumonitis can occur leading to pulmonary insufficiency and death (100% after exposure to 50 gray of radiation) in a few months. Radiation pneumonitis is characterized by:

Symptoms of radiation pneumonitis include: fever, cough, chest congestion, shortness of breath, chest pain

Diagnosis

High resolution CT thorax

Treatment

“The Canadian Cancer society mentions these things that help to manage radiation,

Your healthcare team may recommend medicines to treat radiation pneumonitis, such as:

You can also try the following to help manage symptoms:

Rest if you feel short of breath.

Drink more fluids and use a cool-air vaporizer or humidifier to keep the air moist. Use an extra pillow to raise your head and upper body while resting or sleeping. Avoid the outdoors on hot, humid days or very cold days (which can irritate the lungs). Wear light, loose-fitting tops and avoid anything tight around the neck, such as ties or shirt collars.“ [3]

See also

References

  1. Marks, L; Yu, X; Vujaskovic, Z; Smalljr, W; Folz, R; Anscher, M (July 2003). "Radiation-induced lung injury". Seminars in Radiation Oncology. 13 (3): 333–345. doi:10.1016/S1053-4296(03)00034-1. PMID   12903021.
  2. Palacio, Diana; Jayagurunathan, Usha; Shroff, Girish S.; De Groot, Patricia M.; Truong, Mylene T.; Moran, Cesar A. (2023). "Iatrogenic Conditions". The Thorax. pp. 871–905. doi:10.1007/978-3-031-21040-2_26. ISBN   978-3-031-21039-6.
  3. "Radiation pneumonitis". Canadian Cancer Society. November 2023.

Further reading