Tenatumomab

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Tenatumomab
Monoclonal antibody
Type Whole antibody
Source Mouse
Target Tenascin C
Clinical data
ATC code
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Tenatumomab is a monoclonal antibody designed for the treatment of cancer. [1]

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<span class="mw-page-title-main">Acceleration</span> Rate of change of velocity

In mechanics, acceleration is the rate of change of the velocity of an object with respect to time. Accelerations are vector quantities. The orientation of an object's acceleration is given by the orientation of the net force acting on that object. The magnitude of an object's acceleration, as described by Newton's Second Law, is the combined effect of two causes:

<span class="mw-page-title-main">Kinetic energy</span> Energy of a moving physical body

In physics, the kinetic energy of an object is the form of energy that it possesses due to its motion. It is defined as the work needed to accelerate a body of a given mass from rest to its stated velocity. Having gained this energy during its acceleration, the body maintains this kinetic energy unless its speed changes. The same amount of work is done by the body when decelerating from its current speed to a state of rest. Formally, a kinetic energy is any term in a system's Lagrangian which includes a derivative with respect to time and the second term in a Taylor expansion of a particle's relativistic energy.

<span class="mw-page-title-main">Momentum</span> Property of a mass in motion

In Newtonian mechanics, momentum is the product of the mass and velocity of an object. It is a vector quantity, possessing a magnitude and a direction. If m is an object's mass and v is its velocity, then the object's momentum p is :

In physics, power is the amount of energy transferred or converted per unit time. In the International System of Units, the unit of power is the watt, equal to one joule per second. In older works, power is sometimes called activity. Power is a scalar quantity.

<span class="mw-page-title-main">Special relativity</span> Theory of interwoven space and time by Albert Einstein

In physics, the special theory of relativity, or special relativity for short, is a scientific theory of the relationship between space and time. In Albert Einstein's original treatment, the theory is based on two postulates:

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In mathematics, a tensor is an algebraic object that describes a multilinear relationship between sets of algebraic objects related to a vector space. Tensors may map between different objects such as vectors, scalars, and even other tensors. There are many types of tensors, including scalars and vectors, dual vectors, multilinear maps between vector spaces, and even some operations such as the dot product. Tensors are defined independent of any basis, although they are often referred to by their components in a basis related to a particular coordinate system.

<span class="mw-page-title-main">Electric field</span> Physical field surrounding an electric charge

An electric field is the physical field that surrounds electrically charged particles and exerts force on all other charged particles in the field, either attracting or repelling them. It also refers to the physical field for a system of charged particles. Electric fields originate from electric charges and time-varying electric currents. Electric fields and magnetic fields are both manifestations of the electromagnetic field, one of the four fundamental interactions of nature.

<span class="mw-page-title-main">Probability density function</span> Function whose integral over a region describes the probability of an event occurring in that region

In probability theory, a probability density function (PDF), or density of an absolutely continuous random variable, is a function whose value at any given sample in the sample space can be interpreted as providing a relative likelihood that the value of the random variable would be equal to that sample. Probability density is the probability per unit length, in other words, while the absolute likelihood for a continuous random variable to take on any particular value is 0, the value of the PDF at two different samples can be used to infer, in any particular draw of the random variable, how much more likely it is that the random variable would be close to one sample compared to the other sample.

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The Boltzmann constant is the proportionality factor that relates the average relative thermal energy of particles in a gas with the thermodynamic temperature of the gas. It occurs in the definitions of the kelvin and the gas constant, and in Planck's law of black-body radiation and Boltzmann's entropy formula, and is used in calculating thermal noise in resistors. The Boltzmann constant has dimensions of energy divided by temperature, the same as entropy. It is named after the Austrian scientist Ludwig Boltzmann.

<span class="mw-page-title-main">Schrödinger equation</span> Description of a quantum-mechanical system

The Schrödinger equation is a linear partial differential equation that governs the wave function of a quantum-mechanical system. It is a key result in quantum mechanics, and its discovery was a significant landmark in the development of the subject. The equation is named after Erwin Schrödinger, who postulated the equation in 1925, and published it in 1926, forming the basis for the work that resulted in his Nobel Prize in Physics in 1933.

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In physics, work is the energy transferred to or from an object via the application of force along a displacement. In its simplest form, for a constant force aligned with the direction of motion, the work equals the product of the force strength and the distance traveled. A force is said to do positive work if when applied it has a component in the direction of the displacement of the point of application. A force does negative work if it has a component opposite to the direction of the displacement at the point of application of the force.

<span class="mw-page-title-main">Gibbs free energy</span> Type of thermodynamic potential; useful for calculating reversible work in certain systems

In thermodynamics, the Gibbs free energy is a thermodynamic potential that can be used to calculate the maximum amount of work, other than pressure-volume work, that may be performed by a thermodynamically closed system at constant temperature and pressure. It also provides a necessary condition for processes such as chemical reactions that may occur under these conditions. The Gibbs free energy is expressed as where p is pressure, T is the temperature, U is the internal energy, V is volume, H is the enthalpy, and S is the entropy.

<span class="mw-page-title-main">Michaelis–Menten kinetics</span> Model of enzyme kinetics

In biochemistry, Michaelis–Menten kinetics, named after Leonor Michaelis and Maud Menten, is the simplest case of enzyme kinetics, applied to enzyme-catalysed reactions of one substrate and one product. It takes the form of an equation describing the rate reaction rate to , the concentration of the substrate A. Its formula is given by the Michaelis–Menten equation:

<span class="mw-page-title-main">Time dilation</span> Measured time difference as explained by relativity theory

In physics and relativity, time dilation is the difference in the elapsed time as measured by two clocks. It is either due to a relative velocity between them or to a difference in gravitational potential between their locations. When unspecified, "time dilation" usually refers to the effect due to velocity.

In fluid dynamics, drag is a force acting opposite to the relative motion of any object moving with respect to a surrounding fluid. This can exist between two fluid layers or between a fluid and a solid surface.

In linear algebra, an eigenvector or characteristic vector of a linear transformation is a nonzero vector that changes at most by a scalar factor when that linear transformation is applied to it. The corresponding eigenvalue, often denoted by , is the factor by which the eigenvector is scaled.

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Velocity is the directional speed of an object in motion as an indication of its rate of change in position as observed from a particular frame of reference and as measured by a particular standard of time. Velocity is a fundamental concept in kinematics, the branch of classical mechanics that describes the motion of bodies.

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In mathematics, Hilbert spaces allow generalizing the methods of linear algebra and calculus from (finite-dimensional) Euclidean vector spaces to spaces that may be infinite-dimensional. Hilbert spaces arise naturally and frequently in mathematics and physics, typically as function spaces. Formally, a Hilbert space is a vector space equipped with an inner product that defines a distance function for which the space is a complete metric space.

A transformer is a deep learning model. It is distinguished by its adoption of self-attention, differentially weighting the significance of each part of the input data. It is used primarily in the fields of natural language processing (NLP) and computer vision (CV).

References

  1. International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.