Tarextumab

Last updated
Tarextumab
Monoclonal antibody
Type ?
Source Human
Target Notch 2, Notch 3
Clinical data
Other namesOMP-59R5
ATC code
  • none
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
Formula C6338H9804N1700O1990S48
Molar mass 143196.94 g·mol−1

Tarextumab (formerly OMP-59R5) is a fully human monoclonal antibody targeting the Notch 2/3 receptors. It is being tested as a possible treatment for cancer. In January 2015, the US FDA granted orphan drug designation to tarextumab for the treatment of pancreatic cancer and lung cancer. [1] Two early stage clinical trials have reported encouraging results. [1]

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References

  1. 1 2 "Tarextumab Gets FDA Orphan Drug Designation for Lung, Pancreatic Cancer". 2015.