| 2021 Cleveland Open | |
|---|---|
| Date | 15–21 March |
| Edition | 3rd |
| Surface | Hard (Indoor) |
| Location | Cleveland, Ohio, United States |
| Champions | |
| Singles | |
 Bjorn Fratangelo | |
| Doubles | |
| Robert Galloway / Alex Lawson | |
The 2021 Cleveland Open was a professional tennis tournament played on hard courts. It was the third edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Cleveland, Ohio, United States between March 15 and March 21, 2021. [1]
| Country | Player1 | Rank1 | Seed |
|---|---|---|---|
 AUS | James Duckworth | 103 | 1 |
 JPN | Go Soeda | 144 | 2 |
 ECU | Emilio Gómez | 176 | 3 |
 DEN | Mikael Torpegaard | 190 | 4 |
| USA | Mitchell Krueger | 205 | 5 |
 CAN | Brayden Schnur | 216 | 6 |
| USA | Thai-Son Kwiatkowski | 218 | 7 |
 DOM | Roberto Cid Subervi | 231 | 8 |
The following players received wildcards into the singles main draw:
Liam Draxl Roy Smith Zachary Svajda The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Felix Corwin Alexis Galarneau Aleksandar Kovacevic Evan Song Bjorn Fratangelo def. Jenson Brooksby 7–5, 6–4. Robert Galloway / Alex Lawson def. Evan King / Hunter Reese 7–5, 6–7(5–7), [11–9].
