| 2022 Cleveland Open | |
|---|---|
| Date | January 31 – February 6 |
| Edition | 4th |
| Surface | Hard (indoor) |
| Location | Cleveland, Ohio, United States |
| Champions | |
| Singles | |
 Dominic Stricker | |
| Doubles | |
 William Blumberg / Max Schnur | |
The 2022 Cleveland Open was a professional tennis tournament played on indoor hard courts. It was the fourth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Cleveland, Ohio, United States between January 31 and February 6, 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| USA | Tennys Sandgren | 94 | 1 |
 ITA | Andreas Seppi | 101 | 2 |
 JPN | Yoshihito Nishioka | 119 | 3 |
 GBR | Liam Broady | 128 | 4 |
 AUT | Jurij Rodionov | 137 | 5 |
| USA | Ernesto Escobedo | 141 | 6 |
 ECU | Emilio Gómez | 153 | 7 |
| USA | Jack Sock | 157 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Ulises Blanch 
Sebastian Fanselow
Alexis Galarneau 
Rinky Hijikata Emilio Nava Roberto Quiroz Dominic Stricker def. Yoshihito Nishioka 7–5, 6–1. William Blumberg / Max Schnur def. Robert Galloway / Jackson Withrow 6–3, 7–6(7–4).The 2017 Levene Gouldin & Thompson Tennis Challenger was a professional tennis tournament played on hard court. It was the 24th edition of the tournament which was part of the 2017 ATP Challenger Tour. It took place in Binghamton, United States between 24 and 30 July 2017.
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