| 2022 Open de Oeiras II | |
|---|---|
| Date | 4–10 April |
| Edition | 6th |
| Surface | Clay |
| Location | Oeiras, Portugal |
| Champions | |
| Singles | |
 Gastão Elias | |
| Doubles | |
| Nuno Borges / Francisco Cabral | |
The 2022 Open de Oeiras II was a professional tennis tournament played on clay courts. It was the sixth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Oeiras, Portugal between 4 and 10 April 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 BRA | Thiago Monteiro | 116 | 1 |
 CZE | Zdeněk Kolář | 137 | 2 |
| POR | Nuno Borges | 150 | 3 |
 AUS | Christopher O'Connell | 153 | 4 |
 ITA | Alessandro Giannessi | 174 | 5 |
 KAZ | Dmitry Popko | 175 | 6 |
 SVK | Jozef Kovalík | 184 | 7 |
 BUL | Dimitar Kuzmanov | 191 | 8 |
The following players received wildcards into the singles main draw:
Pedro Araújo Tiago Cação João Domingues The following players received entry from the qualifying draw:
Lucas Gerch Oscar José Gutierrez
Ergi Kırkın Alexandar Lazarov 
Fábián Marozsán 
Alex Rybakov Gastão Elias def. Alessandro Giannessi 7–6(7–4), 6–1. Nuno Borges / Francisco Cabral def. Zdeněk Kolář / Adam Pavlásek 6–4, 6–0.The 2021 Open de Oeiras was a professional tennis tournament played on clay courts. It was the first edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Oeiras, Portugal between 29 March and 3 April 2021.
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