| 2022 Aspria Tennis Cup | |
|---|---|
| Date | 20–26 June |
| Edition | 16th |
| Surface | Clay |
| Location | Milan, Italy |
| Champions | |
| Singles | |
 Federico Coria | |
| Doubles | |
 Luciano Darderi /  Fernando Romboli | |
The 2022 Aspria Tennis Cup was a professional tennis tournament played on clay courts. It was the sixteenth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Milan, Italy between 20 and 26 June 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| ARG | Federico Coria | 64 | 1 |
 FRA | Benoît Paire | 79 | 2 |
 BOL | |||
| ITA | |||
| Alexander Shevchenko | 176 | 5 | |
| ITA | Marco Cecchinato | 206 | 6 |
| ITA | Luciano Darderi | 237 | 7 |
| ITA | Francesco Passaro | 253 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Georgii Kravchenko
Shintaro Mochizuki Federico Coria def. Francesco Passaro 7–6(7–2), 6–4. Luciano Darderi / Fernando Romboli def. 
Diego Hidalgo / 
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