| 2022 Shymkent Challenger II | |
|---|---|
| Date | 16–21 May |
| Edition | 6th |
| Surface | Clay |
| Location | Shymkent, Kazakhstan |
| Champions | |
| Singles | |
 Sergey Fomin | |
| Doubles | |
Sanjar Fayziev /  Markos Kalovelonis | |
The 2022 Shymkent Challenger II was a professional tennis tournament played on clay courts. It was the sixth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Shymkent, Kazakhstan between 16 and 21 May 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| Alexander Shevchenko | 238 | 1 | |
 UKR | Illya Marchenko | 254 | 2 |
 ESP | Nicolás Álvarez Varona | 276 | 3 |
 JPN | Kaichi Uchida | 285 | 4 |
| Evgeny Karlovskiy | 286 | 5 | |
 ROU | Filip Jianu | 295 | 6 |
| UZB | Denis Istomin | 299 | 7 |
 SUI | Antoine Bellier | 311 | 8 |
The following players received wildcards into the singles main draw:
Saba Purtseladze 
Dostanbek Tashbulatov Beibit Zhukayev The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Sergey Fomin 
Ivan Gakhov 
Arjun Kadhe Mukund Sasikumar Eric Vanshelboim
Evan Zhu Sergey Fomin def. 
Robin Haase 7–6(7–4), 6–3. Sanjar Fayziev / Markos Kalovelonis def. 
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