| 2022 Challenger di Roseto degli Abruzzi II | |
|---|---|
| Date | 14–20 March |
| Edition | 2nd |
| Surface | Clay |
| Location | Roseto degli Abruzzi, Italy |
| Champions | |
| Singles | |
 Manuel Guinard | |
| Doubles | |
 Franco Agamenone / Manuel Guinard | |
The 2022 Challenger di Roseto degli Abruzzi II was a professional tennis tournament played on clay courts. It was the second edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Roseto degli Abruzzi, Italy between 14 and 20 March 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 CZE | Jiří Veselý | 74 | 1 |
| ITA | Gianluca Mager | 95 | 2 |
 ESP | Carlos Taberner | 105 | 3 |
| FRA | |||
| ESP | Bernabé Zapata Miralles | 118 | 5 |
 SRB | Nikola Milojević | 126 | 6 |
 SVK | Andrej Martin | 127 | 7 |
 TPE | Tseng Chun-hsin | 159 | 8 |
The following players received wildcards into the singles main draw:
Flavio Cobolli Andrea Del Federico Giulio Zeppieri The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
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