| 2022 Challenger Rio de Janeiro | |
|---|---|
| Date | 10 – 16 October |
| Edition | 1st |
| Surface | Clay |
| Location | Rio de Janeiro, Brazil |
| Champions | |
| Singles | |
 Marco Cecchinato | |
| Doubles | |
 Guido Andreozzi / Guillermo Durán | |
The 2022 Challenger Rio de Janeiro was a professional tennis tournament played on clay courts. It was the first edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Rio de Janeiro, Brazil between 10 and 16 October 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| ARG | Federico Coria | 72 | 1 |
 PER | Juan Pablo Varillas | 107 | 2 |
| ITA | Marco Cecchinato | 114 | 3 |
| ARG | Camilo Ugo Carabelli | 119 | 4 |
 BRA | Felipe Meligeni Alves | 143 | 5 |
 FRA | Alexandre Müller | 145 | 6 |
| ARG | Juan Manuel Cerúndolo | 148 | 7 |
 GER | Yannick Hanfmann | 163 | 8 |
The following players received wildcards into the singles main draw:
Gustavo Almeida João Fonseca João Lucas Reis da Silva The following player received entry into the singles main draw as a special exempt:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Marco Cecchinato def. Yannick Hanfmann 4–6, 6–4, 6–3. Guido Andreozzi / Guillermo Durán def. 
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