| 2022 Challenger Banque Nationale de Drummondville | |
|---|---|
| Date | November 14 – 20 | 
| Edition | 15th | 
| Category | ATP Challenger Tour | 
| Surface | Hard (indoor) | 
| Location | Drummondville, Canada | 
| Champions | |
| Singles | |
|  Vasek Pospisil | |
| Doubles | |
|  Julian Cash /  Henry Patten | |
The 2022 Challenger Banque Nationale de Drummondville was a professional tennis tournament played on indoor hard courts. It was the 15th edition of the tournament and part of the 2022 ATP Challenger Tour. It took place in Drummondville, Canada between November 14 and 20, 2022.
| Country | Player | Rank1 | Seed | 
|---|---|---|---|
|  ECU | Emilio Gómez | 107 | 1 | 
|  USA | Michael Mmoh | 115 | 2 | 
|  CAN | Vasek Pospisil | 118 | 3 | 
|  ARG | Juan Pablo Ficovich | 140 | 4 | 
|  FRA | |||
|  FRA | Antoine Escoffier | 216 | 6 | 
|  CAN | Alexis Galarneau | 222 | 7 | 
|  CAN | Gabriel Diallo | 248 | 8 | 
The following players received wildcards into the singles main draw:
 Taha Baadi
  Taha Baadi  Justin Boulais
  Justin Boulais  Marko Stakusic
  Marko StakusicThe following player received entry into the singles main draw using a protected ranking:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
 Liam Draxl
  Liam Draxl  Maks Kaśnikowski
  Maks Kaśnikowski  Joshua Lapadat
  Joshua Lapadat Max Hans Rehberg
  Max Hans Rehberg  Roy Smith
  Roy Smith Kai Wehnelt
  Kai WehneltThe following player received entry as a lucky loser:
 Constantin Frantzen
  Constantin Frantzen  Roko Horvat
  Roko Horvat Vasek Pospisil  def.
  Vasek Pospisil  def.   Michael Mmoh 7–6(7–5), 4–6, 6–4.
  Michael Mmoh 7–6(7–5), 4–6, 6–4. Julian Cash  /
  Julian Cash  /   Henry Patten  def.
  Henry Patten  def.   Arthur Fery /
  Arthur Fery /   Giles Hussey 6–3, 6–3.
  Giles Hussey 6–3, 6–3.