| 2022 Zadar Open | |
|---|---|
| Date | 21–27 March |
| Edition | 2nd |
| Prize money | €45,730 (2022) |
| Surface | Clay |
| Location | Zadar, Croatia |
| Champions | |
| Singles | |
 Flavio Cobolli | |
| Doubles | |
 Zdeněk Kolář / Andrea Vavassori | |
The 2022 Zadar Open was a professional tennis tournament played on clay courts. It was the second edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Zadar, Croatia between 21 and 27 March 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| ITA | Gianluca Mager | 95 | 1 |
 SRB | Nikola Milojević | 126 | 2 |
 SVK | Andrej Martin | 127 | 3 |
| CZE | Zdeněk Kolář | 138 | 4 |
| ITA | Franco Agamenone | 169 | 5 |
| ITA | Flavio Cobolli | 177 | 6 |
 BUL | Dimitar Kuzmanov | 193 | 7 |
 FRA | Manuel Guinard | 199 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Matteo Arnaldi Riccardo Balzerani
Cezar Crețu 
Daniel Michalski 
Carlos Sánchez Jover Miljan Zekić Flavio Cobolli def. Daniel Michalski 6–4, 6–2. Zdeněk Kolář / Andrea Vavassori def. Franco Agamenone / Manuel Guinard 3–6, 7–6(9–7), [10–6].