| 2022 Challenger La Manche | |
|---|---|
| Date | 7–13 February |
| Edition | 29th |
| Surface | Hard (indoor) |
| Location | Cherbourg, France |
| Champions | |
| Singles | |
 Benjamin Bonzi | |
| Doubles | |
| Jonathan Eysseric / Quentin Halys | |
The 2022 Challenger La Manche was a professional tennis tournament played on indoor hard courts. It was the 29th edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Cherbourg, France between 7 and 13 February 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| FRA | Benjamin Bonzi | 68 | 1 |
| FRA | Pierre-Hugues Herbert | 113 | 2 |
 CZE | Tomáš Macháč | 116 | 3 |
 AUT | Dennis Novak | 117 | 4 |
| FRA | Gilles Simon | 130 | 5 |
| FRA | Quentin Halys | 141 | 6 |
 RUS | Roman Safiullin | 148 | 7 |
| FRA | Lucas Pouille | 156 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
Benjamin Bonzi def. Constant Lestienne 6–4, 2–6, 6–4. Jonathan Eysseric / Quentin Halys def. 
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