| 2022 Challenger Temuco | |
|---|---|
| Date | 21–27 November |
| Edition | 1st |
| Surface | Hard |
| Location | Temuco, Chile |
| Champions | |
| Singles | |
 Guido Andreozzi | |
| Doubles | |
| Guido Andreozzi / Guillermo Durán | |
The 2022 Challenger Temuco was a professional tennis tournament played on hard courts. It was the 1st edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Temuco, Chile between 21 and 27 November 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| ARG | Facundo Bagnis | 103 | 1 |
 ECU | Emilio Gómez | 111 | 2 |
 PER | |||
| ARG | Juan Pablo Ficovich | 136 | 4 |
| ARG | Santiago Rodríguez Taverna | 169 | 5 |
| ARG | Facundo Mena | 177 | 6 |
| ARG | Renzo Olivo | 188 | 7 |
| ARG | Nicolás Kicker | 200 | 8 |
 DOM | Nick Hardt | 219 | 9 |
The following players received wildcards into the singles main draw:
Nicolás Bruna Juan Ignacio Galarza Juan Bautista OteguiThe following players received entry from the qualifying draw:
Guido Andreozzi 
Alafia Ayeni Tomás Farjat Tomás Lipovšek Puches 
Federico Zeballos Matías ZukasThe following player received entry as a lucky loser:
Guido Andreozzi def. Nicolás Kicker 4–6, 6–4, 6–2. Guido Andreozzi / Guillermo Durán def. 
Luis David Martínez / 
Jeevan Nedunchezhiyan 6–4, 6–2.