| 2022 Murcia Open | |
|---|---|
| Date | 4 – 10 April |
| Edition | 3rd |
| Surface | Clay |
| Location | Murcia, Spain |
| Champions | |
| Singles | |
 Tseng Chun-hsin | |
| Doubles | |
 Íñigo Cervantes / Oriol Roca Batalla | |
The 2022 Murcia Open was a professional tennis tournament played on clay courts. It was the 3rd edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Murcia, Spain, between 4 and 10 April 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 SVK | Norbert Gombos | 112 | 1 |
 ARG | Juan Manuel Cerúndolo | 122 | 2 |
 AUT | Dennis Novak | 140 | 3 |
| TPE | Tseng Chun-hsin | 148 | 4 |
| ESP | |||
 GER | Maximilian Marterer | 192 | 6 |
| ARG | Marco Trungelliti | 194 | 7 |
 ITA | Andrea Pellegrino | 196 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Ulises Blanch Miguel Damas
Michael Geerts 
Oleksii Krutykh Daniel Mérida Aguilar Rudolf Molleker The following player received entry as a lucky loser:
Christopher Heyman Tseng Chun-hsin def. Norbert Gombos 6–4, 6–1. Íñigo Cervantes / Oriol Roca Batalla def. Pedro Cachin / 
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