| 2021 Open du Pays d'Aix | |
|---|---|
| Date | 14–20 June |
| Edition | 8th |
| Draw | 32S / 16D |
| Surface | Clay |
| Location | Aix-en-Provence, France |
| Champions | |
| Singles | |
 Carlos Taberner | |
| Doubles | |
 Sadio Doumbia / Fabien Reboul | |
The 2021 Open du Pays d'Aix was a professional tennis tournament played on clay courts. It was the eighth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Aix-en-Provence, France between 14 and 20 June 2021.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| ESP | Roberto Carballés Baena | 95 | 1 |
| ESP | Fernando Verdasco | 99 | 2 |
 ARG | Facundo Bagnis | 104 | 3 |
| ARG | Francisco Cerúndolo | 117 | 4 |
 PER | Juan Pablo Varillas | 130 | 5 |
| ESP | Carlos Taberner | 137 | 6 |
| FRA | Hugo Gaston | 141 | 7 |
 IND | Sumit Nagal | 143 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Oscar José Gutierrez Carlos Taberner def. Manuel Guinard 6–2, 6–2. Sadio Doumbia / Fabien Reboul def. 
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