alkylglycerol kinase | |||||||||
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Identifiers | |||||||||
EC no. | 2.7.1.93 | ||||||||
CAS no. | 55354-37-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an alkylglycerol kinase (EC 2.7.1.93) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are ATP and 1-O-alkyl-sn-glycerol, whereas its two products are ADP and 1-O-alkyl-sn-glycerol 3-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase. Other names in common use include 1-alkylglycerol kinase (phosphorylating), ATP-alkylglycerol phosphotransferase, alkylglycerol phosphotransferase, and ATP: 1-alkyl-sn-glycerol phosphotransferase. This enzyme participates in ether lipid metabolism.
sn-Glycerol 3-phosphate is the organic ion with the formula HOCH2CH(OH)CH2OPO32-. It is one of three stereoisomers of the ester of dibasic phosphoric acid (HOPO32-) and glycerol. It is a component of glycerophospholipids. From a historical reason, it is also known as L-glycerol 3-phosphate, D-glycerol 1-phosphate, L-α-glycerophosphoric acid.
Glycerol kinase, encoded by the gene GK, is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis.
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