DNA primase is an enzyme involved in the replication of DNA and is a type of RNA polymerase. Primase catalyzes the synthesis of a short RNA segment called a primer complementary to a ssDNA template. After this elongation, the RNA piece is removed by a 5' to 3' exonuclease and refilled with DNA.
DNA polymerase subunit gamma is an enzyme that in humans is encoded by the POLG gene. Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE).
Glucosidase 2 subunit beta is an enzyme that in humans is encoded by the PRKCSH gene.
Replication factor C subunit 3 is a protein that in humans is encoded by the RFC3 gene.
Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene.
F-actin-capping protein subunit alpha-1 is a protein that in humans is encoded by the CAPZA1 gene.
Eukaryotic translation initiation factor 2 subunit 3 (eIF2γ) is a protein that in humans is encoded by the EIF2S3 gene.
DNA polymerase delta subunit 2 is an enzyme that in humans is encoded by the POLD2 gene. It is a component of the DNA polymerase delta complex.
Poly(A) polymerase alpha is an enzyme that in humans is encoded by the PAPOLA gene.
Cleavage and polyadenylation specificity factor subunit 4 is a protein that in humans is encoded by the CPSF4 gene.
Actin-related protein 2/3 complex subunit 1A is a protein that in humans is encoded by the ARPC1A gene.
DNA-directed RNA polymerase III subunit RPC10 is an enzyme that in humans is encoded by the POLR3K gene.
DNA polymerase epsilon subunit 3 is an enzyme that in humans is encoded by the POLE3 gene.
DNA-directed RNA polymerase III subunit RPC5 is an enzyme that in humans is encoded by the POLR3E gene.
Integrator complex subunit 9 is a protein that in Humans is encoded by the INTS9 gene.
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma is an enzyme that in humans is encoded by the PPP2R3C gene.
PrimPol is a protein encoded by the PRIMPOL gene in humans. PrimPol is a eukaryotic protein with both DNA polymerase and DNA Primase activities involved in translesion DNA synthesis. It is the first eukaryotic protein to be identified with priming activity using deoxyribonucleotides. It is also the first protein identified in the mitochondria to have translesion DNA synthesis activities.
DNA polymerase alpha subunit 2 is an enzyme that in humans is encoded by the POLA2 gene.
DNA primase small subunit is an enzyme that in humans is encoded by the PRIM1 gene.
DNA polymerase alpha catalytic subunit is an enzyme that in humans is encoded by the POLA1 gene.
