Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate. It is one of the building blocks needed for the synthesis of RNA during the transcription process. Its structure is similar to that of the guanosine nucleoside, the only difference being that nucleotides like GTP have phosphates on their ribose sugar. GTP has the guanine nucleobase attached to the 1' carbon of the ribose and it has the triphosphate moiety attached to ribose's 5' carbon.
Guanylyl transferases are enzymes that transfer a guanosine mono phosphate group, usually from GTP to another molecule, releasing pyrophosphate. Many eukaryotic guanylyl transferases are capping enzymes that catalyze the formation of the 5' cap in the co-transcriptional modification of messenger RNA. Because the 5' end of the RNA molecule ends in a phosphate group, the bond formed between the RNA and the GTP molecule is an unusual 5'-5' triphosphate linkage, instead of the 3'-5' linkages between the other nucleotides that form an RNA strand. In capping enzymes, a highly conserved lysine residue serves as the catalytic residue that forms a covalent enzyme-GMP complex.
In enzymology, a GDP-L-fucose synthase (EC 1.1.1.271) is an enzyme that catalyzes the chemical reaction
In enzymology, an acid—CoA ligase (GDP-forming) is an enzyme that catalyzes the chemical reaction
In enzymology, a succinate—CoA ligase (GDP-forming) is an enzyme that catalyzes the chemical reaction
The enzyme GDP-mannose 4,6-dehydratase (EC 4.2.1.47) catalyzes the chemical reaction
Guanosine diphosphate mannose or GDP-mannose is a nucleotide sugar that is a substrate for glycosyltransferase reactions in metabolism. This compound is a substrate for enzymes called mannosyltransferases.
The enzyme guanosine-3′,5′-bis(diphosphate) 3′-diphosphatase (EC 3.1.7.2) catalyzes the reaction
In enzymology, a dolichyl-phosphate beta-D-mannosyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an adenosylcobinamide-phosphate guanylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a fucokinase is an enzyme that catalyzes the chemical reaction
In enzymology, a glucose-1-phosphate adenylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a glucose-1-phosphate guanylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a guanosine-triphosphate guanylyltransferase (EC 2.7.7.45) is an enzyme that catalyzes the chemical reaction
In enzymology, a mannose-1-phosphate guanylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a mannose-1-phosphate guanylyltransferase (GDP) is an enzyme that catalyzes the chemical reaction
In enzymology, a nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase is an enzyme that catalyzes the chemical reaction
Fucose-1-phosphate guanylyltransferase is an enzyme that in humans is encoded by the FPGT gene.
2-Phospho-L-lactate guanylyltransferase is an enzyme with systematic name GTP:2-phospho-L-lactate guanylyltransferase. This enzyme catalyses the following chemical reaction
D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase is an enzyme with systematic name GTP:D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase. This enzyme catalyses the following chemical reaction
