Glucose-1-phosphate phosphodismutase

glucose-1-phosphate phosphodismutase
Identifiers
EC no.	2.7.1.41
CAS no.	9026-25-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a glucose-1-phosphate phosphodismutase (EC 2.7.1.41) is an enzyme that catalyzes the chemical reaction

2 D-glucose 1-phosphate ⇌ D-glucose + D-glucose 1,6-bisphosphate

Hence, this enzyme has one substrate, D-glucose 1-phosphate, and two products, D-glucose and D-glucose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase. This enzyme participates in glycolysis / gluconeogenesis and starch and sucrose metabolism.

References

• LELOIR LF, TRUCCO RE, et al. (1949). "The formation of glucose diphosphate by Escherichia coli". Arch. Biochem. 24 (1): 65–74. PMID   15400363.
• Sidbury JB, Rosenberg LL, Najjar VA (1956). "Muscle glucose-1-phosphate transphosphorylase". J. Biol. Chem. 222 (1): 89–96. doi: 10.1016/S0021-9258(19)50774-8 . PMID   13366982.