Inositol 3-kinase

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inositol 3-kinase
Identifiers
EC no. 2.7.1.64
CAS no. 37278-07-2
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In enzymology, an inositol 3-kinase (EC 2.7.1.64) is an enzyme that catalyzes the chemical reaction

ATP + myo-inositol ADP + 1D-myo-inositol 3-phosphate

Thus, the two substrates of this enzyme are ATP and myo-inositol, whereas its two products are ADP and 1D-myo-inositol 3-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:myo-inositol 1-phosphotransferase. Other names in common use include inositol-1-kinase (phosphorylating), myoinositol kinase, and myo-inositol 1-kinase. This enzyme participates in inositol phosphate metabolism.

Related Research Articles

<span class="mw-page-title-main">Inositol-3-phosphate synthase</span>

In enzymology, an inositol-3-phosphate synthase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Inositol-phosphate phosphatase</span> Class of enzymes

The enzyme Inositol phosphate-phosphatase is of the phosphodiesterase family of enzymes. It is involved in the phosphophatidylinositol signaling pathway, which affects a wide array of cell functions, including but not limited to, cell growth, apoptosis, secretion, and information processing. Inhibition of inositol monophosphatase may be key in the action of lithium in treating bipolar disorder, specifically manic depression.

In enzymology, a 1-phosphatidylinositol-3-phosphate 5-kinase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">1-phosphatidylinositol 4-kinase</span> Class of enzymes

In enzymology, a 1-phosphatidylinositol 4-kinase is an enzyme that catalyzes the chemical reaction

In enzymology, 1-phosphatidylinositol-4-phosphate 5-kinase is an enzyme that catalyzes the chemical reaction

In enzymology, a 1-phosphatidylinositol-5-phosphate 4-kinase is an enzyme that catalyzes the chemical reaction

In enzymology, a [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] is an enzyme that catalyzes the chemical reaction

In enzymology, a diphosphoinositol-pentakisphosphate kinase is an enzyme that catalyzes the chemical reaction

In enzymology, a fucokinase is an enzyme that catalyzes the chemical reaction

In enzymology, an inositol-pentakisphosphate 2-kinase is an enzyme that catalyzes the chemical reaction

In enzymology, an inositol-tetrakisphosphate 1-kinase is an enzyme that catalyzes the chemical reaction

In enzymology, an inositol-tetrakisphosphate 5-kinase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Inositol-trisphosphate 3-kinase</span> Class of enzymes

Inositol (1,4,5) trisphosphate 3-kinase (EC 2.7.1.127), abbreviated here as ITP3K, is an enzyme that facilitates a phospho-group transfer from adenosine triphosphate to 1D-myo-inositol 1,4,5-trisphosphate. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase. ITP3K catalyzes the transfer of the gamma-phosphate from ATP to the 3-position of inositol 1,4,5-trisphosphate to form inositol 1,3,4,5-tetrakisphosphate. ITP3K is highly specific for the 1,4,5-isomer of IP3, and it exclusively phosphorylates the 3-OH position, producing Ins(1,3,4,5)P4, also known as inositol tetrakisphosphate or IP4.

In enzymology, a phosphatidylinositol-4,5-bisphosphate 3-kinase is an enzyme that catalyzes the chemical reaction:

In enzymology, a phosphatidylinositol-4-phosphate 3-kinase is an enzyme that catalyzes the chemical reaction

In enzymology, a scyllo-inosamine 4-kinase is an enzyme that catalyzes the chemical reaction

Bisphosphate may refer to:

Inositol-polyphosphate multikinase is an enzyme with systematic name ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase. This enzyme catalyses the following chemical reaction

inositol-1,3,4-trisphosphate 5/6-kinase is an enzyme with systematic name ATP:1D-myo-inositol 1,3,4-trisphosphate 5-phosphotransferase. This enzyme catalyses the following chemical reaction

Inositol-hexakisphosphate kinase is an enzyme with systematic name ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase. This enzyme catalyses the following chemical reaction

References


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