Scheduled airlines
| Airline | Image | IATA | ICAO | Fleet | Founded | Type |
|---|---|---|---|---|---|---|
| Uzbekistan Airways [1] |  | HY [2] | UZB [2] | A20N A21N A320 [3] A321 [3] A330 [3] PC-24 [3] | 1992 [4] | Flag Carrier [5] |
| Qanot Sharq [6] | HH [6] | QNT [6] | A320 [7] A321 [7] | 1998 [8] | Scheduled | |
| Centrum Air [9] [10] | C6 [11] | MFX | A320 [12] A32N A21N A330 | 2023 [12] | Low-Cost [10] | |
| FlyOne Asia [13] | 7Q | AUV | A320 | 2025 | Low-Cost | |
| My Freighter [14] | C6 [14] | MFX [14] | A320F A21NF B747F B767F [15] | 2021 [15] | Freighter [14] | |
| 5P [16] | UZP [16] | A320 [17] | 2021 [18] | Suspended [19] | ||
| Tashkent Air [20] | TSK [20] | A330 | 2022 | Long-Haul | ||
| Air Samarkand [21] |  | 9S [22] | UZS [23] | A321 A21N A330 [24] | 2022 [25] | Scheduled |
| Silk Avia [26] | US [27] | USA | ATR-72 [28] | 2021 [26] | Regional | |
| SpaceBee Airlines [29] | Y3 [30] | UZU | B767F [31] | 2022 [32] | Freighter [33] | |
| Fly Khiva [34] |  | 2U [35] | FKH | B767F B753 [36] | 2021 | Freighter, [37] Scheduled [38] |
