Tom Blundell (British, 1942–) — crystal structures of HIV protease, renin, insulin and other hormones, growth factors, receptors, and proteins important in cell signalling and DNA repair; developed structure-guided and fragment-based approaches to drug design
Charles Cantor (1942–) — Director, Center for Advanced Biotechnology, Boston University. Cantor is a molecular geneticist who developed pulse field electrophoresis for very large DNA molecules with David C. Schwartz in 1984, by adding an alternating voltage gradient to standard gel electrophoresis.
Carolyn Cohen (American, 1929–2017} — in 1969, Cohen codiscovered the molecular structure of tropomyosin as a polar coiled coil, also being the first protein crystal structure determined with a 20Å resolution via x-ray crystallography. On the route to this discovery, she also discovered a novel crystal structure, termed the Cohen-Longley paracrystal with 400Å periodicity, in 1966.
Christoph Cremer — overcoming the conventional limit of resolution that applies to light based investigations (the Abbe limit) by a range of different methods like SPDM and SMI
Max Delbrück (German, American, 1906–1981) — discovered that bacteria become resistant to phages as a result of genetic mutations. Delbrück, Salvador Luria, and Alfred Hershey shared the 1969 Nobel Prize in Physiology or Medicine "for their discoveries concerning the replication mechanism and the genetic structure of viruses"
Joachim Frank (German and American, 1940–) — pioneered single-particle reconstruction in electron microscopy; studied structure and dynamics of ribosomes.[2]
Richard Henderson (British, 1945–) — scientist at the MRC Laboratory of Molecular Biology, developed the use of cryo-EM to study membrane protein structures.
Jagadish Chandra Bose (Indian, 1858–1937) — biologist, physicist, botanist, and an early writer of science fiction
Louise Johnson (English, 1940–2012) — Crystal structure of lysozyme (1st enzyme) with David Phillips, then glycogen phosphorylase. Wrote influential crystallography textbook with Tom Blundell.[4]
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John Kendrew with model of myoglobin in progress. Brian Kobilka
Stephen D. Levene (American) — DNA-protein Interactions, DNA looping, and DNA topology
Michael Levitt (South African, British, American and Israeli, 1947–) — winner of the 2013 Nobel Prize in Chemistry (with Arieh Warshel) for the development of multiscale models for complex chemical systems[5]
Nicolas Rashevsky (American of Ukrainian origin, 1899–1972),[8] former Editor of the first journal of mathematical and theoretical biophysics entitled " The Bulletin of Mathematical Biophysics " (1940–1973) and author of the two-factor model of neuronal excitation, biotopology and organismic set theory
Jacques Ricard (French, 1928–2018) — enzymologist known for the concept of enzyme memory
Frederic M. Richards (American, 1925–2009) — crystal structure of the ribonuclease S
Jane Richardson (American, 1941–) — developed the ribbon diagram for representing the 3D structure of proteins; with husband David, developed MolProbity structure-validation web service
Michael Rossmann (German and American, 1930–2019) — worked with Max Perutz on the crystal structure of hemoglobin, then in his own lab solved structures of enzymes including lactate dehydrogenase, the prototype of the Rossmann fold, and of many viruses including the common cold virus.
Benoît Roux (Canadian, PhD 1990) — classical molecular dynamics and other theoretical techniques to determine the molecular function of biological systems.
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Erich Sackmann (German, 1934–2024) — founder of the bottom-up approach to understanding of the cell mechanics and adhesion
Arieh Warshel (Israeli-born American, 1940–) — development of QM/MM approaches for a quantitative understanding of enzymatic reactions; introduction of molecular dynamics simulations in biology; introduction of consistent electrostatic calculations in proteins.
James D. Watson (American, 1928–) — co-discoverer of the structure of DNA.
Anthony Watts (British, 1950–) — early proponent of the idea of both structural and functional significance of “Lipid-protein interactions”, and developer of solid state NMR for biology.
Watt W. Webb (American, 1927–2020) — developer of multiphoton microscopy
Gregorio Weber (Argentinian, 1916–1997) fluorescence spectroscopy and protein chemistry
King-Wai Yau (Chinese-born American, 1948–) — fundamental contributions to understanding the mechanisms of sensory transduction in rod, cone, and non-image visual systems and in olfaction
Ada Yonath (Israeli, 1939–) — winner of the 2009 Nobel Prize in Chemistry (with Steitz and Ramakrishnan) for solving the crystal structure of the large subunit of the ribosome
Douglas Youvan (American, 1955–) — light reactions of photosynthesis, genetic code, imaging spectroscopy and directed evolution
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