- Oreochromis amphimelas of lakes, often saline, in north–central Tanzania
- Oreochromis andersonii, a threatened species of south–central Africa
- Oreochromis leucostictus of Albertine Rift Valley lakes and introduced elsewhere
- Oreochromis lidole, a possibly extinct species of the Lake Malawi basin
- Oreochromis macrochir, a threatened species of south–central Africa
- Oreochromis mossambicus, a widespread species that also is introduced outside its native range
- Oreochromis niloticus, a very widespread species that also is introduced outside its native range
- Oreochromis squamipinnis, a threatened species of the Lake Malawi basin
- Oreochromis variabilis, a threatened species of the Lake Victoria basin
- Oreochromis alcalica, formerly allocated to Alcolapia