RNA uridylyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.7.7.52 | ||||||||
CAS no. | 78519-53-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a RNA uridylyltransferase (EC 2.7.7.52) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are UTP and RNA n, whereas its two products are diphosphate and RNAn+1.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:RNA uridylyltransferase. Other names in common use include terminal uridylyltransferase, and TUT.
As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 2E5G, 2IKF, 2NOM, 2Q0C, 2Q0D, 2Q0E, 2Q0F, and 2Q0G.
Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth. Nucleotides are obtained in the diet and are also synthesized from common nutrients by the liver.
A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups from one molecule to another. They are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of life's most important processes.
UTP—glucose-1-phosphate uridylyltransferase also known as glucose-1-phosphate uridylyltransferase is an enzyme involved in carbohydrate metabolism. It synthesizes UDP-glucose from glucose-1-phosphate and UTP; i.e.,
In enzymology, an arginine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a RNA-3′-phosphate cyclase is an enzyme that catalyzes the chemical reaction
In enzymology, an ATP phosphoribosyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a glucuronate-1-phosphate uridylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a mRNA guanylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a [protein-PII] uridylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an [RNA-polymerase]-subunit kinase is an enzyme that catalyzes the chemical reaction
In enzymology, a sulfate adenylyltransferase (ADP) (EC 2.7.7.5) is an enzyme that catalyzes the chemical reaction
In enzymology, a thiamine-diphosphate kinase is an enzyme involved in thiamine metabolism. It catalyzes the chemical reaction
CCA tRNA nucleotidyltransferase is an enzyme with systematic name CTP,CTP,ATP:tRNA cytidylyl,cytidylyl,adenylyltransferase. This enzyme catalyses the following chemical reaction
In enzymology, a tRNA nucleotidyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an UDP-glucose—hexose-1-phosphate uridylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an UDP-N-acetylglucosamine diphosphorylase is an enzyme that catalyzes the chemical reaction
In enzymology, an UTP—hexose-1-phosphate uridylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an UTP-monosaccharide-1-phosphate uridylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an UTP—xylose-1-phosphate uridylyltransferase is an enzyme that catalyzes the chemical reaction
Terminal uridylyltransferase 7 (TUT7), also known as "zinc finger, CCHC domain containing 6", is an enzyme that in humans is encoded by the ZCCHC6 gene located on chromosome 9. The ZCCHC6 protein mediates the terminal uridylation of RNA transcripts with short poly-A tails and is involved in mRNA and microRNA degradation