Phossy jaw, formally known as phosphorus necrosis of the jaw, was an occupational disease affecting those who worked with white phosphorus without proper safeguards. It is also likely to occur as the result of use of chemical weapons that contain white phosphorus. It was most commonly seen in workers in the matchstick industry in the 19th and early 20th centuries. It was caused by white phosphorus vapor, which destroys the bones of the jaw. Modern occupational hygiene practices have since eliminated the working conditions that caused this disease.
Ebenezer McBurney Byers was an American socialite, sportsman, and industrialist. He won the 1906 U.S. Amateur in golf. He died from jawbone cancer after consuming Radithor, a patent medicine made from radium salts dissolved in water.
The Radium Girls were female factory workers who contracted radiation poisoning from painting radium dials – watch dials and hands with self-luminous paint. The incidents occurred at three factories in the United States: one in Orange, New Jersey, beginning around 1917; one in Ottawa, Illinois, beginning in the early 1920s; and one in Waterbury, Connecticut, also in the 1920s.
Radithor was a patent medicine that is a well-known example of radioactive quackery. It consisted of triple-distilled water containing at a minimum 1 microcurie (37 kBq) each of the radium 226 and 228 isotopes.
Radioluminescence is the phenomenon by which light is produced in a material by bombardment with ionizing radiation such as alpha particles, beta particles, or gamma rays. Radioluminescence is used as a low level light source for night illumination of instruments or signage. Radioluminescent paint is occasionally used for clock hands and instrument dials, enabling them to be read in the dark. Radioluminescence is also sometimes seen around high-power radiation sources, such as nuclear reactors and radioisotopes.
Luminous paint is paint that emits visible light through fluorescence, phosphorescence, or radioluminescence.
Cherubism is a rare genetic disorder that causes prominence in the lower portion in the face. The name is derived from the temporary chubby-cheeked resemblance to putti, the chubby-faced infants featured in Renaissance paintings, which were often mistakenly described as cherubs.
Radium dials are watch, clock and other instrument dials painted with luminous paint containing radium-226 to produce radioluminescence. Radium dials were produced throughout most of the 20th century before being replaced by safer tritium-based luminous material in the 1970s and finally by non-toxic, non-radioactive strontium aluminate–based photoluminescent material from the middle 1990s.
Osteonecrosis of the jaw (ONJ) is a severe bone disease (osteonecrosis) that affects the jaws. Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature.
Undark was a trade name for luminous paint made with a mixture of radioactive radium and zinc sulfide, as produced by the U.S. Radium Corporation between 1917 and 1938. It was used primarily in watch and clock dials. The people working in the industry who applied the radioactive paint became known as the Radium Girls because many of them became ill and some died from exposure to the radiation emitted by the radium contained within the product. The product was the direct cause of radium jaw in the dial painters. Undark was also available as a kit for general consumer use and marketed as glow-in-the-dark paint.
The United States Radium Corporation was a company, most notorious for its operations between the years 1917 to 1926 in Orange, New Jersey, in the United States that led to stronger worker protection laws. After initial success in developing a glow-in-the-dark radioactive paint, the company was subject to several lawsuits in the late 1920s in the wake of severe illnesses and deaths of workers who had ingested radioactive material. The workers had been told that the paint was harmless. During World War I and World War II, the company produced luminous watches and gauges for the United States Army for use by soldiers.
Radiobiology is a field of clinical and basic medical sciences that involves the study of the effects of ionizing radiation on living things, in particular health effects of radiation. Ionizing radiation is generally harmful and potentially lethal to living things but can have health benefits in radiation therapy for the treatment of cancer and thyrotoxicosis. Its most common impact is the induction of cancer with a latent period of years or decades after exposure. High doses can cause visually dramatic radiation burns, and/or rapid fatality through acute radiation syndrome. Controlled doses are used for medical imaging and radiotherapy.
Mandibular fracture, also known as fracture of the jaw, is a break through the mandibular bone. In about 60% of cases the break occurs in two places. It may result in a decreased ability to fully open the mouth. Often the teeth will not feel properly aligned or there may be bleeding of the gums. Mandibular fractures occur most commonly among males in their 30s.
A jaw abnormality is a disorder in the formation, shape and/or size of the jaw. In general abnormalities arise within the jaw when there is a disturbance or fault in the fusion of the mandibular processes. The mandible in particular has the most differential typical growth anomalies than any other bone in the human skeleton. This is due to variants in the complex symmetrical growth pattern which formulates the mandible.
William John Aloysius Bailey was an American patent medicine inventor and salesman. A Harvard University dropout, Bailey falsely claimed to be a doctor of medicine and promoted the use of radioactive radium as a cure for coughs, flu, and other common ailments. Although Bailey's Radium Laboratories in East Orange, New Jersey, was continually investigated by the Federal Trade Commission, he died wealthy from his many devices and products, including an aphrodisiac called Arium, marketed as a restorative that "renewed happiness and youthful thrill into the lives of married peoples whose attractions to each other had weakened."
In jawed vertebrates, the mandible, lower jaw, or jawbone is a bone that makes up the lower – and typically more mobile – component of the mouth.
Cysts of the jaws are cysts—pathological epithelial-lined cavities filled with fluid or soft material—occurring on the bones of the jaws, the mandible and maxilla. Those are the bones with the highest prevalence of cysts in the human body, due to the abundant amount of epithelial remnants that can be left in the bones of the jaws. The enamel of teeth is formed from ectoderm, and so remnants of epithelium can be left in the bone during odontogenesis. The bones of the jaws develop from embryologic processes which fuse, and ectodermal tissue may be trapped along the lines of this fusion. This "resting" epithelium is usually dormant or undergoes atrophy, but, when stimulated, may form a cyst. The reasons why resting epithelium may proliferate and undergo cystic transformation are generally unknown, but inflammation is thought to be a major factor. The high prevalence of tooth impactions and dental infections that occur in the bones of the jaws is also significant to explain why cysts are more common at these sites.
Osteoradionecrosis (ORN) is a serious complication of radiation therapy in cancer treatment where radiated bone becomes necrotic and exposed. ORN occurs most commonly in the mouth during the treatment of head and neck cancer, and can arise over 5 years after radiation. Common signs and symptoms include pain, difficulty chewing, trismus, mouth-to-skin fistulas and non-healing ulcers.
Osteomyelitis of the jaws is osteomyelitis which occurs in the bones of the jaws. Historically, osteomyelitis of the jaws was a common complication of odontogenic infection. Before the antibiotic era, it was frequently a fatal condition.
Theodor Blum was a pioneer in local anesthesia, in the use of x-rays in dental care, and in the management of many pathologic oral conditions. He has been described as “the most outstanding oral surgeon in America.” He was a founder of The New York Institute of Clinical Oral Pathology. Through his work and a few others, oral pathology gained recognition as a medical specialty. He was the first to make use in medical literature of the term “radium jaw” that arose from a case he treated that is described in the book The Radium Girls (2016).
