D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase

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D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
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EC no. 2.7.7.70
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D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase (EC 2.7.7.70, D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase, D-glycero-D-manno-heptose-1beta-phosphate adenylyltransferase, hldE (gene), rfaE (gene)) is an enzyme with systematic name ATP:D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase. [1] [2] [3] [4] This enzyme catalyses the following chemical reaction

D-glycero-beta-D-manno-heptose 1-phosphate + ATP ADP-D-glycero-beta-D-manno-heptose + diphosphate

The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose.

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D-glycero-beta-D-manno-heptose-7-phosphate kinase is an enzyme with systematic name ATP:D-glycero-beta-D-manno-heptose 7-phosphate 1-phosphotransferase. This enzyme catalyses the following chemical reaction

D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase may refer to:

HldE may refer to:

RfaE (gene) may refer to:

RFAE may refer to:

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References

  1. Valvano MA, Marolda CL, Bittner M, Glaskin-Clay M, Simon TL, Klena JD (January 2000). "The rfaE gene from Escherichia coli encodes a bifunctional protein involved in biosynthesis of the lipopolysaccharide core precursor ADP-L-glycero-D-manno-heptose". Journal of Bacteriology. 182 (2): 488–97. doi:10.1128/jb.182.2.488-497.2000. PMC   94300 . PMID   10629197.
  2. Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P (January 2002). "Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli". Journal of Bacteriology. 184 (2): 363–9. doi:10.1128/jb.184.2.363-369.2002. PMC   139585 . PMID   11751812.
  3. Valvano MA, Messner P, Kosma P (July 2002). "Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides". Microbiology. 148 (Pt 7): 1979–89. doi: 10.1099/00221287-148-7-1979 . PMID   12101286.
  4. Wang L, Huang H, Nguyen HH, Allen KN, Mariano PS, Dunaway-Mariano D (February 2010). "Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB)". Biochemistry. 49 (6): 1072–81. doi:10.1021/bi902018y. PMC   2844805 . PMID   20050615.