Dephospho-CoA kinase

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dephospho-CoA kinase
Identifiers
EC no. 2.7.1.24
CAS no. 9026-83-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
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NCBI proteins

In enzymology, a dephospho-CoA kinase (EC 2.7.1.24) is an enzyme that catalyzes the chemical reaction

ATP + dephospho-CoA ADP + CoA

Thus, the two substrates of this enzyme are ATP and dephospho-CoA, whereas its two products are ADP and CoA.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:dephospho-CoA 3'-phosphotransferase. Other names in common use include dephosphocoenzyme A kinase (phosphorylating), 3'-dephospho-CoA kinase, and dephosphocoenzyme A kinase. This enzyme participates in pantothenate and coa biosynthesis.

Structural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1JJV, 1N3B, 1T3H, 1VHL, 1VHT, 1VIY, 2GRJ, and 2IF2.

Related Research Articles

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References


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