Evan Flatow

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Evan Flatow
Born (1956-03-21) March 21, 1956 (age 69)
New York City
Nationality American
Alma mater Princeton University, Columbia University College of Physicians and Surgeons
Known for shoulder surgery, scientist, researcher
AwardsThe Neer Award for Excellence in Shoulder Research, American Shoulder and Elbow Surgeons, 1992, 1994, 1996, 2004

Lifetime Achievement Award, New York Chapter, Arthritis Foundation, 2009

Elected to College of Fellows, American Institute for Medical and Biological Engineering, 2010

Contents

Scientific career
Fields orthopaedic surgeon
InstitutionsFormer President, Mount Sinai West (retired 2024)

Evan Flatow (born March 21, 1956) is an American orthopaedic surgeon-scientist. Until retiring 2024, he was President of Mount Sinai West (formerly Mount Sinai Roosevelt), part of the Mount Sinai Health System. He published more than 400 book chapters and peer-reviewed articles. [1] [2] Flatow is indicated as principal or co-principal investigator for nine research grants and listed on six patents for influential shoulder implant systems. [3] [4]

Before Flatow's appointment at Mount Sinai West, he served as the Bernard J. Lasker Professor and Chair of the Leni and Peter W. May Department of Orthopaedic Surgery at Icahn School of Medicine at Mount Sinai, where he established a basic science tendon research group in the Orthopaedic Research Laboratory, and he also served as Director of the Orthopaedic Surgery Service at Mount Sinai Hospital in New York City. [5] He was chosen by Castle Connolly as one of America's top doctors [6] and has won the American Shoulder and Elbow Surgeons' Neer Award, its highest honor, four times. [7] [8] He is the President of the Board of Trustees of St. Hilda's & St. Hugh's, where he graduated in 1973.

Career

Flatow graduated from Princeton University with an A.B. in biomedical sciences in 1977 after completing a 39-page long senior thesis titled "The Comparative Biochemistry of Microtubule Accessory Proteins." [9] He earned his medical degree from the Columbia University College of Physicians and Surgeons in 1981 and completed a surgical residency at St. Luke's-Roosevelt Hospital Center and an orthopaedic residency and fellowship at Columbia-Presbyterian Medical Center. [8]

In 1998, after 11 years on the faculty at Columbia University, Flatow joined the staff at Mount Sinai Hospital. He was Chair of Orthopaedics from 2005 until 2014, and then President of Mount Sinai West, a position he held until 2024. In collaboration with Mount Sinai's Department of Anesthesiology, Flatow pioneered the use of regional blocks to diminish the need for general anesthesia in shoulder surgery. [5] [8]

He held positions as Chair of the Trustees of the Journal of Shoulder and Elbow Surgery, and Chair of the Publications Committee and of the Council on Education of the American Academy of Orthopaedic Surgeons. [10] [11] He also served as President of American Shoulder & Elbow Surgeons. [12]

Scientific contributions

Grants

As of 2023, Flatow was Principal Investigator (PI) or Co-Principal on 11 research grants. Partial list:

Patents

Flatow co-developed humeral stem and glenoid socket designs and procedures for coated and uncoated shoulder replacements. The process requires minimal bone resection and as of 2023 is used globally [11] in total shoulder arthroplasty. [16] [17] Patents include:

Developments and implications

Flatow focuses on minimally invasive fracture repair, arthroscopic rotator cuff surgery, arthroscopic repair and shoulder replacement. [24] Developments include:

Shoulder articular geometry and kinematics: Flatow contributed to the development of a glenoid implant with dual-curvatures allowing central conformity with low contact stress. [25]

Cadaver studies of rotator cuff tendon injury: demonstrated the effects of subacromial compression and tensile load on the supraspinatus tendon, with implications for clinical failure. [26] [27] [28]

Clinical outcome studies of rotator cuff tendon repair: rotator cuff tendon failure and repair, demonstration that cuff-tendon repair was a cost-effective procedure, that re-tears were common, and that muscle atrophy did not recover after tendon repair. [29]

Development of a rat infrapatellar tendon repetitive fatigue-damage model of tendon injury: collaborated to refine histologic and imaging techniques to assess tendon damage. [30] [31] [32]

Characterization of the mechanical and biologic response of tendon to repetitive fatigue damage, and the effect of exercise.Demonstrated that damage is permanent, apoptosis resulted, and fatigued tendon failed to mount a robust biologic and reparative response. [33] [34] [35]

Honors and awards

Publications

Flatow is a reviewer for Clinical Orthopaedics and Related Research, the Journal of Bone and Joint Surgery, Arthroscopy, the Journal of Orthopaedic Research, and the American Journal of Sports Medicine. He is the former North American editor and chair, board of trustees, for the Journal of Shoulder and Elbow Surgery. He is a reviewer for that journal as of 2022.

Books

Peer reviewed publications

As of 2023, Flatow was cited 22,600 times, has an h-index of 81and an i10-index of 194. [36]

Highest cited (partial list):

Most recent:

References

  1. ↑ "Flatow EL - Search Results - PubMed". PubMed. Retrieved 2022-01-26.
  2. ↑ "Evan Flatow". scholar.google.com. Retrieved 2023-02-12.
  3. ↑ "A century of shoulder arthroplasty innovations and discoveries". www.healio.com. Retrieved 2022-02-04.
  4. ↑ Flatow, E.; Harrison, A. (2011). "A History of Reverse Total Shoulder Arthroplasty". Clinical Orthopaedics and Related Research. 469 (9): 2432–2439. doi:10.1007/s11999-010-1733-6. PMC   3148354 . PMID   21213090. S2CID   33062066.
  5. 1 2 "Mount Sinai Hospital – Doctor profile". Mount Sinai Hospital.
  6. ↑ "Castle Connolly Medical Ltd". Archived from the original on June 30, 2009. Retrieved January 17, 2010.
  7. ↑ "American Shoulder and Elbow Surgeons". Becker's Hospital Review. Archived from the original on October 22, 2007. Retrieved January 17, 2010.
  8. 1 2 3 "Ten Shoulder Specialists to Know: Becker's Hospital Review". Archived from the original on June 30, 2009. Retrieved January 17, 2010.
  9. ↑ Flatow, Evan Lloyd (1977). "The Comparative Biochemistry of Microtubule Accessory Proteins".{{cite journal}}: Cite journal requires |journal= (help)
  10. ↑ "AAOS Media Center". www.aaos-annualmeeting-presskit.org. Retrieved 2023-02-13.
  11. 1 2 "LEADERS Interview with Evan L. Flatow, MD, President, Mount Sinai West". www.leadersmag.com. Retrieved 2023-02-13.
  12. ↑ "The Top 28 North American Shoulder Surgeons" (PDF). Orthopedics This Week. September 24, 2013. Retrieved February 12, 2023.
  13. ↑ Blevins, F. T.; Djurasovic, M.; Flatow, E. L.; Vogel, K. G. (1997). "Biology of the rotator cuff tendon". The Orthopedic Clinics of North America. 28 (1): 1–16. doi:10.1016/s0030-5898(05)70260-1. ISSN   0030-5898. PMID   9024427.
  14. ↑ "RePORT ⟩ RePORTER". reporter.nih.gov. Retrieved 2023-02-13.
  15. ↑ Klein, Kristine (2022-08-25). "NYCEDC announces $26.6 million grant for two new life sciences facilities". The Architect’s Newspaper. Retrieved 2023-02-12.
  16. ↑ Godenèche, Arnaud; Garret, Jérôme; Barth, Johannes; Michelet, Aude; Geais, Laurent (2019-02-20). "Comparison of revision rates and radiographic observations of long and short, uncoated and coated humeral stem designs in total shoulder arthroplasty". EFORT Open Reviews. 4 (2): 70–76. doi:10.1302/2058-5241.4.180046. ISSN   2058-5241. PMC   6404789 . PMID   30931151.
  17. ↑ David M. Levy, MD, Joshua A. Metzl, MD, G. Christian Vorys, MD, William N. Levine, MD, Christopher S. Ahmad, MD, and Louis U. Bigliani, MD. "Clinical and Radiographic Outcomes of Total Shoulder Arthroplasty With a Hybrid Dual-Radii Glenoid Component" (PDF). American Journal of Orthopedics. Retrieved February 15, 2023.{{cite web}}: CS1 maint: multiple names: authors list (link)
  18. ↑ US 5928285,Bigliani, Louis U.; Flatow, Evan L.& Norman, Delfreda L.,"Orthopaedic implant having an articulating surface with a conforming and translational surface",published 1999-07-27, assigned to Bristol-Meyers Squibb Co.
  19. ↑ US 5928285,Bigliani, Louis U.; Flatow, Evan L.& Norman, Delfreda L.,"Orthopaedic implant having an articulating surface with a conforming and translational surface",published 1999-07-27, assigned to Bristol-Meyers Squibb Co.
  20. ↑ US 6017306,Bigliani, Louis U.; Flatow, Evan L.& Norman, Delfreda L.et al.,"Clamp assembly for use with orthopaedic retractor frame assembly",published 2000-01-25, assigned to Bristol-Meyers Squibb Co.
  21. ↑ US 6120507,Allard, Randall N.; Willard, David B.& Flatow, Evan L.,"Instrument and method for seating prosthesis",published 2000-09-19, assigned to Bristol-Meyers Squibb Co.
  22. ↑ US 7699853,Durand-Allen, Anitra; Wiley, Roy& Bigliani, Louiset al.,"Method and instruments for positioning humeral component during shoulder arthroplasty",published 2010-04-20, assigned to Zimmer Inc.
  23. ↑ US 10874748,Sun, Hui B.; Flatow, Evan L.& Wanich, Tonyet al.,"Intervention for tendinopathy",published 2020-12-29, assigned to Albert Einstein College of Medicine,and Icahn School of Medicine at Mount Sinai & Montefiore Medical Center
  24. ↑ Keenan, John (2018-06-06). "Orthopaedic resident graduation events Friday". Newsroom. Retrieved 2023-02-12.
  25. ↑ Ehresmann, K R; Mills, W A; Loewenson, P R; Moore, K A (2000). "Attitudes and practices regarding varicella vaccination among physicians in Minnesota: implications for public health and provider education". American Journal of Public Health. 90 (12): 1917–1920. doi:10.2105/ajph.90.12.1917. ISSN   0090-0036. PMC   1446435 . PMID   11111266.
  26. ↑ Flatow, E. L.; Soslowsky, L. J.; Ticker, J. B.; Pawluk, R. J.; Hepler, M.; Ark, J.; Mow, V. C.; Bigliani, L. U. (1994). "Excursion of the rotator cuff under the acromion. Patterns of subacromial contact". The American Journal of Sports Medicine. 22 (6): 779–788. doi:10.1177/036354659402200609. hdl: 2027.42/67283 . ISSN   0363-5465. PMID   7856802. S2CID   11577634.
  27. ↑ Huang, Chun-Yuh; Wang, Vincent M.; Pawluk, Robert J.; Bucchieri, John S.; Levine, William N.; Bigliani, Louis U.; Mow, Van C.; Flatow, Evan L. (2005). "Inhomogeneous mechanical behavior of the human supraspinatus tendon under uniaxial loading". Journal of Orthopaedic Research. 23 (4): 924–930. doi: 10.1016/j.orthres.2004.02.016 . ISSN   0736-0266. PMID   16023009. S2CID   12121653.
  28. ↑ Huang, Chun-Yuh; Wang, Vincent M.; Flatow, Evan L.; Mow, Van C. (2009-03-11). "Temperature-dependent viscoelastic properties of the human supraspinatus tendon". Journal of Biomechanics. 42 (4): 546–549. doi:10.1016/j.jbiomech.2008.11.013. ISSN   1873-2380. PMC   2684675 . PMID   19159888.
  29. ↑ Bishop, Julie; Klepps, Steven; Lo, Ian K.; Bird, Justin; Gladstone, James N.; Flatow, Evan L. (2006). "Cuff integrity after arthroscopic versus open rotator cuff repair: a prospective study". Journal of Shoulder and Elbow Surgery. 15 (3): 290–299. doi:10.1016/j.jse.2005.09.017. ISSN   1058-2746. PMID   16679227.
  30. ↑ Laudier, Damien; Schaffler, Mitchell B.; Flatow, Evan L.; Wang, Vincent M. (2007). "Novel procedure for high-fidelity tendon histology". Journal of Orthopaedic Research. 25 (3): 390–395. doi: 10.1002/jor.20304 . ISSN   0736-0266. PMID   17149746. S2CID   21816985.
  31. ↑ Fung, David T.; Wang, Vincent M.; Andarawis-Puri, Nelly; Basta-Pljakic, Jelena; Li, Yonghui; Laudier, Damien M.; Sun, Hui B.; Jepsen, Karl J.; Schaffler, Mitchell B.; Flatow, Evan L. (2010-01-19). "Early response to tendon fatigue damage accumulation in a novel in vivo model". Journal of Biomechanics. 43 (2): 274–279. doi:10.1016/j.jbiomech.2009.08.039. ISSN   1873-2380. PMC   3366582 . PMID   19939387.
  32. ↑ Fung, David T.; Sereysky, Jedd B.; Basta-Pljakic, Jelena; Laudier, Damien M.; Huq, Rumana; Jepsen, Karl J.; Schaffler, Mitchell B.; Flatow, Evan L. (2010). "Second harmonic generation imaging and Fourier transform spectral analysis reveal damage in fatigue-loaded tendons". Annals of Biomedical Engineering. 38 (5): 1741–1751. doi:10.1007/s10439-010-9976-7. ISSN   1573-9686. PMC   4785269 . PMID   20232150.
  33. ↑ Sun, Hui B.; Andarawis-Puri, Nelly; Li, Yonghui; Fung, David T.; Lee, Jonathan Y.; Wang, Vincent M.; Basta-Pljakic, Jelena; Leong, Daniel J.; Sereysky, Jedd B.; Ros, Stephen J.; Klug, Raymond A. (2010). "Cycle-dependent matrix remodeling gene expression response in fatigue-loaded rat patellar tendons". Journal of Orthopaedic Research. 28 (10): 1380–1386. doi:10.1002/jor.21132. ISSN   1554-527X. PMC   4408775 . PMID   20839322.
  34. ↑ Andarawis-Puri, Nelly; Sereysky, Jedd B.; Jepsen, Karl J.; Flatow, Evan L. (2012-01-03). "The relationships between cyclic fatigue loading, changes in initial mechanical properties, and the in vivo temporal mechanical response of the rat patellar tendon". Journal of Biomechanics. 45 (1): 59–65. doi:10.1016/j.jbiomech.2011.10.008. ISSN   1873-2380. PMC   3763928 . PMID   22055428.
  35. ↑ Andarawis-Puri, Nelly; Philip, Anaya; Laudier, Damien; Schaffler, Mitchell B.; Flatow, Evan L. (2014). "Temporal effect of in vivo tendon fatigue loading on the apoptotic response explained in the context of number of fatigue loading cycles and initial damage parameters". Journal of Orthopaedic Research. 32 (9): 1097–1103. doi:10.1002/jor.22639. ISSN   1554-527X. PMC   4209741 . PMID   24838769.
  36. ↑ "Evan Flatow". scholar.google.com. Retrieved 2022-01-26.
  37. ↑ "Fatty infiltration and atrophy of the rotator cuff do not improve after rotator cuff repair and correlate with poor functional outcome". scholar.google.com. Retrieved 2023-02-13.
  38. ↑ "Excursion of the rotator cuff under the acromion: patterns of subacromial contact". scholar.google.com. Retrieved 2023-02-13.
  39. ↑ White, Christopher A.; Duey, Akiro; Parsons, Bradford O.; Flatow, Evan L.; Cagle, Paul J. (2023-06-01). "Anatomic total shoulder arthroplasty outcomes and implant survivability at greater than 22 years postoperative follow-up: A case series". Journal of Orthopaedic Reports. 2 (2): 100129. doi: 10.1016/j.jorep.2022.100129 . ISSN   2773-157X. S2CID   255636585.
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