Galactose-1-phosphate thymidylyltransferase

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galactose-1-phosphate thymidylyltransferase
Identifiers
EC no. 2.7.7.32
CAS no. 9023-25-0
Databases
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BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
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Gene Ontology AmiGO / QuickGO
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In enzymology, a galactose-1-phosphate thymidylyltransferase (EC 2.7.7.32) is an enzyme that catalyzes the chemical reaction

dTTP + alpha-D-galactose 1-phosphate diphosphate + dTDP-galactose

Thus, the two substrates of this enzyme are dTTP and alpha-D-galactose 1-phosphate, whereas its two products are diphosphate and dTDP-galactose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase. Other names in common use include dTDP galactose pyrophosphorylase, galactose 1-phosphate thymidylyl transferase, thymidine diphosphogalactose pyrophosphorylase, thymidine triphosphate:alpha-D-galactose 1-phosphate, and thymidylyltransferase. This enzyme participates in nucleotide sugars metabolism.

Related Research Articles

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References


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