Gamma-Renin

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Gamma-renin
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EC no. 3.4.21.54
CAS no. 85270-20-8
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Gamma-renin (EC 3.4.21.54) is an enzyme. [1] [2] This enzyme catalyses the following chemical reaction

Cleavage of the Leu-Leu bond in synthetic renin substrate (horse), to produce angiotensin I, but not active on natural angiotensinogen

This enzyme is present in submandibular glands of male mice.

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References

  1. Poe M, Wu JK, Florance JR, Rodkey JA, Bennett CD, Hoogsteen K (February 1983). "Purification and properties of renin and gamma-renin from the mouse submaxillary gland". The Journal of Biological Chemistry. 258 (4): 2209–16. PMID   6337154.
  2. Drinkwater CC, Evans BA, Richards RI (June 1988). "Sequence and expression of mouse gamma-renin". The Journal of Biological Chemistry. 263 (18): 8565–8. PMID   3288617.