| # | Weekend End Date | Film | Total Weekend Gross | Notes |
|---|
| 1 | January 4, 2009 | Madagascar: Escape 2 Africa(5) | $16,479,785 | (animated film) |
| 2 | January 11, 2009 | Seven Pounds | $15,227,577 | |
| 3 | January 18, 2009 | Seven Pounds(2) | $16,627,449 | |
| 4 | January 25, 2009 | Italians | $17,232,915 | Italy |
| 5 | February 1, 2009 | Italians(2) | $14,181,736 | |
| 6 | February 8, 2009 | Ex | $14,234,973 | Italy |
| 7 | February 15, 2009 | The Curious Case of Benjamin Button | $13,757,206 | |
| 8 | February 22, 2009 | The Curious Case of Benjamin Button(2) | $11,002,656 | |
| 9 | March 1, 2009 | Confessions of a Shopaholic | $11,673,142 | |
| 10 | March 8, 2009 | Watchmen | $10,009,424 | |
| 11 | March 15, 2009 | La matassa | $10,859,021 | Italy |
| 12 | March 22, 2009 | La matassa(2) | $10,428,016 | |
| 13 | March 29, 2009 | Gran Torino | $10,626,358 | |
| 14 | April 5, 2009 | Monsters Vs. Aliens | $10,901,881 | |
| 15 | April 12, 2009 | Monsters Vs. Aliens(2) | $9,017,099 | |
| 16 | April 19, 2009 | Fast & Furious | $12,566,311 | |
| 17 | April 26, 2009 | Fast & Furious(2) | $8,802,525 | |
| 18 | May 3, 2009 | X-Men Origins: Wolverine | $9,435,025 | |
| 19 | May 10, 2009 | My Bloody Valentine 3-D | $7,757,474 | |
| 20 | May 17, 2009 | Angels & Demons | $12,218,881 | |
| 21 | May 24, 2009 | Angels & Demons(2) | $7,530,834 | |
| 22 | May 31, 2009 | Angels & Demons(3) | $8,280,204 | |
| 23 | June 7, 2009 | Terminator Salvation | $6,735,340 | |
| 24 | June 14, 2009 | Un'estate ai Caraibi | $4,063,324 | Italy |
| 25 | June 21, 2009 | Coraline | $5,943,567 | |
| 26 | June 28, 2009 | Transformers: Revenge of the Fallen | $7,686,538 | |
| 27 | July 5, 2009 | Transformers: Revenge of the Fallen(2) | $3,948,800 | (animated film) |
| 28 | July 12, 2009 | Transformers: Revenge of the Fallen(3) | $2,684,048 | |
| 29 | July 19, 2009 | Harry Potter and the Half Blood Prince | $8,279,359 | |
| 30 | July 26, 2009 | Harry Potter and the Half Blood Prince(2) | $3,380,500 | |
| 31 | August 2, 2009 | Harry Potter and the Half Blood Prince(3) | $2,186,274 | |
| 32 | August 9, 2009 | Harry Potter and the Half Blood Prince(4) | $1,592,236 | |
| 33 | August 16, 2009 | Sex Drive | $1,429,964 | |
| 34 | August 23, 2009 | The Haunting in Connecticut | $2,201,023 | |
| 35 | August 30, 2009 | Ice Age: Dawn of the Dinosaurs | $11,635,843 | (animated film) |
| 36 | September 6, 2009 | Ice Age: Dawn of the Dinosaurs(2) | $11,970,968 | |
| 37 | September 13, 2009 | Ice Age: Dawn of the Dinosaurs(3) | $11,564,622 | |
| 38 | September 20, 2009 | Ice Age: Dawn of the Dinosaurs(4) | $10,643,616 | |
| 39 | September 27, 2009 | Baarìa - La porta del vento | $11,563,669 | Italy |
| 40 | October 4, 2009 | Baarìa - La porta del vento(2) | $12,048,513 | |
| 41 | October 11, 2009 | Inglourious Basterds | $10,815,564 | |
| 42 | October 18, 2009 | Up | $12,854,374 | |
| 43 | October 25, 2009 | Up(2) | $13,088,258 | |
| 44 | November 1, 2009 | Up(3) | $12,396,074 | |
| 45 | November 8, 2009 | Public Enemies | $12,616,168 | |
| 46 | November 15, 2009 | 2012 | $16,056,246 | |
| 47 | November 22, 2009 | The Twilight Saga: New Moon | $19,331,055 | |
| 48 | November 29, 2009 | Cado dalle Nubi | $15,933,084 | Italy |
| 49 | December 6, 2009 | A Christmas Carol | $15,241,779 | |
| 50 | December 13, 2009 | A Christmas Carol(2) | $10,209,251 | |
| 51 | December 20, 2009 | Natale a Beverly Hills | $12,657,706 | Italy |
| 52 | December 27, 2009 | Natale a Beverly Hills | | |
