| # | Weekend end date | Film | Gross | Notes | Refs |
|---|
| 1 | January 5, 2020 | Star Wars: The Rise of Skywalker | $34,524,815 | | [2] |
| 2 | January 12, 2020 | 1917 | $37,000,200 | 1917 reached the #1 spot after two weeks of limited release. | [3] |
| 3 | January 19, 2020 | Bad Boys for Life | $62,504,105 | Bad Boys for Life had the highest weekend debut of 2020. | [4] |
| 4 | January 26, 2020 | $34,011,714 | | [5] |
| 5 | February 2, 2020 | $17,682,959 | Bad Boys for Life became the first film in 2020 to top the box office for three consecutive weekends. | [6] |
| 6 | February 9, 2020 | Birds of Prey | $33,010,017 | | [7] |
| 7 | February 16, 2020 | Sonic the Hedgehog | $58,018,348 | Sonic the Hedgehog broke Detective Pikachu 's record ($54.4 million) for the highest weekend debut for a video game adaptation. | [8] |
| 8 | February 23, 2020 | $26,192,294 | | [9] |
| 9 | March 1, 2020 | The Invisible Man | $28,205,665 | | [10] |
| 10 | March 8, 2020 | Onward | $39,119,861 | | [11] |
| 11 | March 15, 2020 | $10,601,952 | During the week, Sonic the Hedgehog ($145.0 million) broke Detective Pikachu 's record ($144.1 million) for the highest grossing video game adaptation domestically. | [12] |
| 12–33 | March 22, 2020–August 16, 2020 | These are weekends for which most box office reporting was suspended due to the COVID-19 pandemic following the closure of theaters | [13] |
| 34 | August 23, 2020 | Unhinged | $4,000,761 | Unhinged reached number one in its second weekend of release (and first in American theaters). It was the first wide release film since March. | [14] |
| 35 | August 30, 2020 | The New Mutants | $7,037,017 | | [15] |
| 36 | September 6, 2020 | Tenet | $9,353,090 | With 65% of theaters in the country open, Tenet reached number one, and was highest-grossing weekend for a film since March. | [16] |
| 37 | September 13, 2020 | $6,603,467 | | [17] |
| 38 | September 20, 2020 | $4,568,470 | | [18] |
| 39 | September 27, 2020 | $3,348,340 | Tenet became the first film since Black Panther to top the box office for four consecutive weekends. | [19] |
| 40 | October 4, 2020 | $2,664,202 | Tenet became the first film since Black Panther to top the box office for five consecutive weekends. | [20] |
| 41 | October 11, 2020 | The War with Grandpa | $3,623,880 | | [21] |
| 42 | October 18, 2020 | Honest Thief | $4,115,249 | | [22] |
| 43 | October 25, 2020 | $2,354,022 | | [23] |
| 44 | November 1, 2020 | Come Play | $3,119,875 | | [24] |
| 45 | November 8, 2020 | Let Him Go | $4,000,470 | | [25] |
| 46 | November 15, 2020 | Freaky | $3,600,355 | | [26] |
| 47 | November 22, 2020 | $1,281,150 | | [27] |
| 48 | November 29, 2020 | The Croods: A New Age | $9,724,200 | | [28] |
| 49 | December 6, 2020 | $4,439,855 | | [29] |
| 50 | December 13, 2020 | $3,060,535 | | [30] |
| 51 | December 20, 2020 | Monster Hunter | $2,201,269 | | [31] |
| 52 | December 27, 2020 | Wonder Woman 1984 | $16,701,957 | Simultaneously released on HBO Max. | [32] |