| # | Weekend end date | Film | Box office | Notes | Ref |
|---|
| 1 | January 5, 2003 | The Lord of the Rings: The Two Towers | $25,017,279 | | [3] |
| 2 | January 12, 2003 | Just Married | $17,548,993 | | [4] |
| 3 | January 19, 2003 | Kangaroo Jack | $16,580,209 | | [5] [6] |
| 4 | January 26, 2003 | Darkness Falls | $12,024,917 | | [7] |
| 5 | February 2, 2003 | The Recruit | $16,302,063 | | [8] |
| 6 | February 9, 2003 | How to Lose a Guy in 10 Days | $23,774,850 | | [9] |
| 7 | February 16, 2003 | Daredevil | $40,310,419 | Daredevil broke John Q. 's record ($20.3 mil) for the highest President's Day weekend debut, and Hannibal 's record ($29.7 mil) for the highest President's Day weekend gross. | [10] [11] |
| 8 | February 23, 2003 | $18,092,309 | | [12] |
| 9 | March 2, 2003 | Cradle 2 the Grave | $16,521,468 | | [13] |
| 10 | March 9, 2003 | Bringing Down the House | $31,101,026 | | [14] |
| 11 | March 16, 2003 | $22,054,934 | | [15] |
| 12 | March 23, 2003 | $16,204,468 | | [16] |
| 13 | March 30, 2003 | Head of State | $13,503,484 | | [17] |
| 14 | April 6, 2003 | Phone Booth | $15,021,088 | | [18] |
| 15 | April 13, 2003 | Anger Management | $42,220,847 | Anger Management broke The Scorpion King 's record ($36.1 mil) for the highest weekend debut in April. | [19] |
| 16 | April 20, 2003 | $25,005,588 | | [20] [21] |
| 17 | April 27, 2003 | Identity | $16,225,263 | | [22] |
| 18 | May 4, 2003 | X2 | $85,558,731 | | [23] |
| 19 | May 11, 2003 | $40,032,160 | | [24] |
| 20 | May 18, 2003 | The Matrix Reloaded | $91,774,413 | The Matrix Reloaded's $37.5 million opening day gross broke Star Wars: Episode II – Attack of the Clones ' record ($30.1 mil) for the highest-grossing Thursday of all-time. It also broke Hannibal 's record ($58.0 mil) for the highest weekend debut for an R-rated film and Harry Potter and the Sorcerer's Stone 's record ($90.2 mill) for the highest opening for a Warner Bros. film. The Matrix Reloaded had the highest weekend debut of 2003. | [25] |
| 21 | May 25, 2003 | Bruce Almighty | $67,953,330 | | [26] [27] |
| 22 | June 1, 2003 | Finding Nemo † | $70,251,710 | Finding Nemo broke Monsters, Inc.'s records ($62.6 mil) for the highest weekend debut for an animated film, a non-sequel animated film, a G-rated film, as well as for an original film overall. | [28] |
| 23 | June 8, 2003 | 2 Fast 2 Furious | $50,472,480 | | [29] |
| 24 | June 15, 2003 | Finding Nemo † | $28,384,483 | Finding Nemo reclaimed #1 in its third weekend of release. | [30] |
| 25 | June 22, 2003 | Hulk | $62,128,420 | Hulk broke Austin Powers: The Spy Who Shagged Me 's record ($54.9 mil) for the highest weekend debut in June. | [31] |
| 26 | June 29, 2003 | Charlie's Angels: Full Throttle | $37,634,221 | | [32] |
| 27 | July 6, 2003 | Terminator 3: Rise of the Machines | $44,041,440 | | [33] |
| 28 | July 13, 2003 | Pirates of the Caribbean: The Curse of the Black Pearl | $46,630,690 | | [34] |
| 29 | July 20, 2003 | Bad Boys II | $46,522,560 | | [35] |
| 30 | July 27, 2003 | Spy Kids 3-D: Game Over | $33,417,739 | Spy Kids 3-D: Game Over broke Jaws 3-D 's record ($13.3 mil) for the highest weekend debut for a 3-D film. | [36] |
| 31 | August 3, 2003 | American Wedding | $33,369,440 | | [37] |
| 32 | August 10, 2003 | S.W.A.T. | $37,062,535 | | [38] |
| 33 | August 17, 2003 | Freddy vs. Jason | $36,428,066 | Freddy vs. Jason broke Scream 3 's record ($34.7 million) for the highest weekend debut for a slasher film. | [39] |
| 34 | August 24, 2003 | $13,152,967 | | [40] |
| 35 | August 31, 2003 | Jeepers Creepers 2 | $15,269,324 | Jeepers Creepers 2 broke Jeepers Creepers ' record ($13.1 mil) for the highest Labor Day weekend debut. | [41] [42] |
| 36 | September 7, 2003 | Dickie Roberts: Former Child Star | $6,660,540 | | [43] |
| 37 | September 14, 2003 | Once Upon a Time in Mexico | $23,424,118 | | [44] |
| 38 | September 21, 2003 | Underworld | $21,753,759 | | [45] |
| 39 | September 28, 2003 | The Rundown | $18,553,765 | | [46] |
| 40 | October 5, 2003 | School of Rock | $19,622,714 | | [47] |
| 41 | October 12, 2003 | Kill Bill: Volume 1 | $22,089,322 | | [48] [49] |
| 42 | October 19, 2003 | The Texas Chainsaw Massacre | $28,094,014 | | [50] |
| 43 | October 26, 2003 | Scary Movie 3 | $48,113,770 | Scary Movie 3 broke Red Dragon 's record ($36.5 mil) for the highest weekend debut in October as well as for any fall release, and broke Lara Croft: Tomb Raider 's record ($47.7 million) for highest weekend debut for a film featuring a female protagonist. | [51] |
| 44 | November 2, 2003 | $20,017,468 | | [52] |
| 45 | November 9, 2003 | The Matrix Revolutions | $48,475,154 | | [53] |
| 46 | November 16, 2003 | Elf | $26,325,613 | Elf reached #1 in its second weekend of release. | [54] |
| 47 | November 23, 2003 | The Cat in the Hat | $38,329,160 | | [55] |
| 48 | November 30, 2003 | $24,459,685 | | [56] |
| 49 | December 7, 2003 | The Last Samurai | $24,271,354 | | [57] |
| 50 | December 14, 2003 | Something's Gotta Give | $16,064,723 | | [58] |
| 51 | December 21, 2003 | The Lord of the Rings: The Return of the King | $72,629,713 | The Lord of the Rings: The Return of the King's $34.4 million opening day gross broke Star Wars: Episode I – The Phantom Menace 's record ($28.5 mil) for the highest Wednesday gross of all-time. It also broke The Lord of the Rings: The Two Towers ' record ($62.0 mil) for the highest weekend debut in December. | [59] |
| 52 | December 28, 2003 | $50,598,104 | | [60] |