This is a list of films which placed number-one at the weekend box office in Colombia during 2021. [1] Amounts are in American dollars.
| # | Weekend end date | Film | Box office |
|---|---|---|---|
| 1 | January 3, 2021 | Wonder Woman 1984 | $204,882 |
| 2 | January 10, 2021 | $56,658 | |
| 3 | January 17, 2021 | Greenland | $49,563 |
| 4 | January 24, 2021 | $52,351 | |
| 5 | January 31, 2021 | $71,914 | |
| 6 | February 7, 2021 | $69,532 | |
| 7 | February 14, 2021 | Tom & Jerry | $179,315 |
| 8 | February 21, 2021 | $187,225 | |
| 9 | February 28, 2021 | $221,066 | |
| 10 | March 7, 2021 | $168,200 | |
| 11 | March 14, 2021 | $150,262 | |
| 12 | March 21, 2021 | $121,936 | |
| 13 | March 28, 2021 | Raya and the Last Dragon | $24,205 |
| Rank | Title | Distributor | Domestic gross |
|---|---|---|---|
| 1 | Tom & Jerry | Warner Bros. | $1,295,517 |
| 2 | Wonder Woman 1984 | $810,434 | |
| 3 | Greenland | N/A | $602,241 |
| 4 | Monster Hunter | Sony | $501,522 |
| 5 | Chaos Walking | N/A | $353,866 |
| 6 | Raya and the Last Dragon | Disney | $350,929 |
| 7 | The Little Things | Warner Bros. | $189,542 |
| 8 | Redcon-1 | N/A | $107,562 |
| 9 | Malasaña 32 | $105,575 | |
| 10 | Freaky | Universal | $78,408 |