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This is a list of films which placed number-one at the weekend box office in Australia during 2001. Amounts are in Australian dollars.
N/A denotes information that is not available from Urban Cinefile nor Movie Marshal.
| # | Weekend End Date | Film | Box Office | Notes |
|---|---|---|---|---|
| 1 | 7 January 2001 | Meet the Parents | $3,232,242 | |
| 2 | 14 January 2001 | What Women Want | $5,117,384 | |
| 3 | 21 January 2001 | Cast Away | $4,539,061 | |
| 4 | 28 January 2001 | $3,627,587 | ||
| 5 | 4 February 2001 | $2,150,152 | ||
| 6 | 11 February 2001 | $1,392,345 | ||
| 7 | 18 February 2001 | Hannibal | $4,247,648 | Hannibal set a record February opening and a record for an age-restricted film [1] |
| 8 | 25 February 2001 | $1,785,493 | ||
| 9 | 4 March 2001 | Proof of Life | $1,502,269 | |
| 10 | 11 March 2001 | Traffic | $2,616,932 | |
| 11 | 18 March 2001 | Miss Congeniality | $4,330,856 | |
| 12 | 25 March 2001 | $3,473,454 | ||
| 13 | 1 April 2001 | $1,999,690 | ||
| 14 | 8 April 2001 | Save the Last Dance | $1,587,517 | |
| 15 | 15 April 2001 | Crocodile Dundee in Los Angeles | $2,257,164 | |
| 16 | 22 April 2001 | Rugrats in Paris: The Movie | $2,156,887 | Rugrats in Paris: The Movie reached number one in its fourth week of release |
| 17 | 29 April 2001 | The Mexican | $1,839,550 | |
| 18 | 6 May 2001 | $1,093,477 | ||
| 19 | 13 May 2001 | The Mummy Returns | $5,440,204 | |
| 20 | 20 May 2001 | $3,227,374 | ||
| 21 | 27 May 2001 | Moulin Rouge! | $3,655,261 | |
| 22 | 3 June 2001 | $3,589,500 | ||
| 23 | 10 June 2001 | Pearl Harbor | $6,680,157 | |
| 24 | 17 June 2001 | $2,976,993 | ||
| 25 | 24 June 2001 | Lara Croft: Tomb Raider | $5,105,317 | |
| 26 | 1 July 2001 | Shrek | $3,273,603 | Shrek reached number one in its fourth week on the chart [2] |
| 27 | 8 July 2001 | $3,169,980 | ||
| 28 | 15 July 2001 | $3,085,851 | ||
| 29 | 22 July 2001 | $2,102,945 | ||
| 30 | 29 July 2001 | Bridget Jones's Diary | $3,926,141 | |
| 31 | 5 August 2001 | $2,952,549 | ||
| 32 | 12 August 2001 | Planet of the Apes | $3,981,914 | |
| 33 | 19 August 2001 | $2,131,017 | ||
| 34 | 26 August 2001 | A Knight's Tale | $2,233,374 | |
| 35 | 2 September 2001 | Jurassic Park III | $3,742,739 | |
| 36 | 9 September 2001 | $2,053,941 | ||
| 37 | 16 September 2001 | A.I. Artificial Intelligence | $1,591,000 | |
| 38 | 23 September 2001 | The Fast and the Furious | $3,300,893 | |
| 39 | 30 September 2001 | Rush Hour 2 | $4,334,524 | |
| 40 | 7 October 2001 | Cats & Dogs | $2,691,589 | Cats & Dogs reached number one in its third week of release [3] |
| 41 | 14 October 2001 | Legally Blonde | $2,539,971 | |
| 42 | 21 October 2001 | Scary Movie 2 | $1,507,503 | |
| 43 | 28 October 2001 | The Man Who Sued God | $1,530,832 | |
| 44 | 4 November 2001 | $1,341,408 | ||
| 45 | 11 November 2001 | The Others | $2,570,457 | |
| 46 | 18 November 2001 | $1,787,925 | ||
| 47 | 25 November 2001 | N/A | The Others grossed $1,690,869 for the week ended 28 November [4] | |
| 48 | 2 December 2001 | Harry Potter and the Philosopher's Stone | $9,249,505 | |
| 49 | 9 December 2001 | $5,157,175 | ||
| 50 | 16 December 2001 | $3,207,844 | ||
| 51 | 23 December 2001 | $2,279,772 | ||
| 52 | 30 December 2001 | The Lord of the Rings: The Fellowship of the Ring | $9,749,937 | |
