The following is a list of independent pharmaceutical, biotechnology and medical companies listed on a stock exchange (as indicated) that have generated a revenue of at least US$10 billion, ranked by their revenue in the respective financial year.
It does not include biotechnology companies that are now owned by, or form a part of, larger pharmaceutical groups.
The following table lists the largest biotechnology and pharmaceutical companies ranked by revenue in billion USD. The change column indicates the company's relative position in this list compared to its relative position in the preceding year; i.e., an increase would be moving closer to rank 1 and vice versa. Green cells indicate years where revenue increased compared to the preceding year. Red cells indicate those years when there has been a decrease.
Rank | Chg | Company | Country | Traded on | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Johnson & Johnson | USA | NYSE : JNJ | 88.82 [1] | 85.16 [2] | 79.99 [2] | 93.78 [3] | 82.59 [3] | 82.06 [4] | 81.60 [5] | 76.50 [6] | 71.89 [7] | 70.10 [8] | |
2 | Sinopharm | CHN | SEHK : 1099 | 84.06 [9] | 80.19 [10] | 75.68 [10] | 71.75 [11] | 60.18 [12] | 48.75 [13] | 43.63 [14] | 36.56 [15] | 32.36 [16] | ||
3 | Roche | SUI | SIX : ROG | 66.42 [17] | 68.48 [18] | 69.77 [19] | 67.83 [20] | 62.99 [20] | 63.85 [21] | 56.86 [22] | 57.37 [23] | 50.11 [24] | 47.70 [25] | |
4 | Merck & Co. | USA | NYSE : MRK | 64.17 [26] | 60.12 [27] | 59.28 [28] | 48.70 [29] | 41.52 [29] | 46.84 [30] | 42.30 [31] | 40.10 [32] | 39.80 [33] | 39.50 [34] | |
5 | Pfizer | USA | NYSE : PFE | 63.63 [35] | 59.55 [35] | 100.33 [36] | 81.29 [37] | 41.91 [38] | 41.17 [38] | 40.83 [38] | 52.54 [39] | 52.82 [40] | 48.85 [41] | |
6 | AbbVie | USA | NYSE : ABBV | 56.33 [42] | 54.32 [43] | 58.05 [44] | 56.20 [45] | 45.80 [45] | 33.27 [46] | 32.75 [47] | 28.22 [48] | 25.56 [49] | 22.82 [50] | |
7 | Bayer | GER | FWB : BAYN | 51.72 [51] | 53.88 [52] | 49.46 [53] | 47.40 [54] | 48.02 [55] | 45.06 [56] | 37.94 [57] | 25.27 [58] | 24.09 [59] | ||
8 | 2 | Novartis | SUI | NYSE : NVS | 50.32 [60] | 45.44 [61] | 50.55 [62] | 51.63 [63] | 48.66 [63] | 47.45 [64] | 44.75 [65] | 49.11 [66] | 48.52 [67] | 49.41 [68] |
9 | 1 | Sanofi | FRA | NYSE : SNY | 42.68 [69] | 46.84 [70] | 46.86 [71] | 43.24 [72] | 41.27 [73] | 39.28 [74] | 39.07 [75] | 42.91 [76] | 36.57 [77] | 36.73 [78] |
10 | 1 | AstraZeneca | GBR SWE | LSE : AZN | 45.81 [79] | 44.35 [80] | 37.42 [81] | 26.62 [82] | 24.38 [83] | 22.09 [84] | 22.47 [85] | 23.00 [86] | 24.71 [87] | |
11 | Bristol Myers Squibb | USA | Nasdaq : BMY | 45.01 [88] | 46.16 [89] | 46.39 [90] | 42.52 [90] | 26.15 [91] | 22.56 [92] | 20.80 [93] | 19.43 [94] | 16.56 [95] | ||
12 | Abbott Laboratories | USA | Nasdaq : ABT | 41.95 [96] | 40.11 [97] | 43.65 [98] | 43.08 [99] | 34.61 [100] | 31.90 [101] | 30.60 [102] | 27.39 [103] | 20.85 [104] | 20.41 [105] | |
13 | 3 | Novo Nordisk | DEN | NYSE : NVO | 40.52 [106] | 33.83 [107] | 25.46 [108] | 21.66 [109] | 19.52 [109] | 18.30 [110] | 6.99 [111] | 18.77 [112] | 16.61 [113] | 16.06 [114] |
14 | 1 | GlaxoSmithKline | GBR | LSE : GSK | 39.28 [115] | 38.63 [116] | 36.14 [117] | 46.91 [118] | 46.17 [119] | 43.92 [120] | 43.14 [121] | 42.05 [122] | 34.79 [123] | 29.84 [124] |
15 | 1 | Shanghai Pharmaceuticals | CHN | SSE : 601607 | 36.68 [125] | 32.33 [126] | 31.82 [127] | 29.29 [127] | 27.50 [127] | 23.45 [127] | 19.28 [127] | 17.80 [128] | 15.55 [128] | |
16 | 1 | Eli Lilly & Co | USA | NYSE : LLY | 34.12 [129] | 28.54 [130] | 28.32 [131] | 24.54 [132] | 22.32 [133] | 21.49 [134] | 22.90 [135] | 21.22 [136] | 20.00 [137] | |
17 | Takeda Pharmaceutical | JPN | TYO : 4502 | 30.24 [138] | 30.34 [139] | 29.31 [140] | 27.76 [141] | 31.17 [142] | 19.10 [143] | 16.70 [144] | 15.96 [145] | 14.93 | ||
18 | Amgen | USA | Nasdaq : AMGN | 33.42 [146] | 28.19 [147] | 26.32 [148] | 25.98 [149] | 25.42 [150] | 23.40 [151] | 23.70 [152] | 22.80 [153] | 22.99 [154] | 21.66 [155] | |
19 | Boehringer Ingelheim | GER | Private | 27.70 [156] | 25.90 [157] | 22.50 [158] | 22.40 [159] | 21.75 [160] | 21.67 [161] | 17.54 [162] | 16.41 [162] | 17.70 [162] | ||
20 | Gilead Sciences | USA | Nasdaq : GILD | 27.12 [163] | 27.28 [164] | 27.31 [164] | 24.69 [165] | 22.45 [166] | 22.13 [167] | 25.70 [168] | 30.39 [168] | 32.15 [168] | ||
21 | 1 | Siemens Healthineers | GER | FWB : SHL | 23.32 [169] | 23.09 [170] | 20.61 [171] | 16.56 [171] | 16.62 [172] | 15.37 [173] | 16.56 [174] | 14.25 [174] | 14.06 [174] | |
22 | 1 | Merck Group | GER | ETR: MRK | 22.79 [175] | 23.64 [176] | 21.40 [177] | 20.08 [178] | 18.25 [179] | 16.48 [180] | 18.70 [181] | 16.62 [182] | 14.25 [183] | |
23 | Jointown Pharmaceutical | CHN | SSE : 600998 | 21.15 [184] | 19.81 [185] | 18.04 [186] | 16.34 [187] | 14.67 [188] | 12.85 [189] | 10.90 [190] | 9.07 [191] | 7.31 [192] | ||
24 | GE Healthcare | USA | Nasdaq : GEHC | 19.55 [193] | 18.34 [194] | 17.73 [195] | 18.01 [196] | 19.94 [197] | 19.78 [197] | 19.02 [197] | 18.21 [197] | 17.64 [197] | ||
25 | Teva Pharmaceuticals | ISR | Nasdaq : TEVA | 16.54 [198] | 15.85 [199] | 14.93 [200] | 15.88 [201] | 16.66 [202] | 16.89 [203] | 18.90 [204] | 22.40 [205] | 21.90 [206] | 20.00 [207] | |
26 | Kenvue | USA | NYSE : KVUE | 15.44 [208] | 14.95 [208] | |||||||||
27 | Viatris | USA | Nasdaq : VTRS | 15.43 [209] | 16.22 [210] | 17.81 [210] | 11.95 [211] | |||||||
28 | Baxter International | USA | NYSE : BAX | 14.81 [212] | 15.11 [213] | 12.78 [214] | 11.63 [215] | 11.36 [215] | 11.13 [216] | 10.56 [216] | 10.16 [217] | 9.97 [218] | ||
29 | Haleon | GBR | LSE : HLN | 14.29 [219] | 13.14 [220] | 11.77 [221] | ||||||||
30 | Otsuka Holdings | JPN | TYO : 4578 | 14.23 [222] | 13.05 [223] | 11.65 [224] | 11.06 [224] | 10.85 [224] | 10.04 [224] | 9.64 [224] | 9.29 [224] | 11.10 [224] | ||
31 | Regeneron Pharmaceuticals | USA | Nasdaq : REGN | 14.20 [225] | 13.12 [226] | 12.17 [227] | 16.07 [228] | 8.50 [228] | 7.86 [229] | 6.71 [229] | 5.87 [229] | 4.86 [230] | 4.10 [231] | |
32 | Astellas Pharma | JPN | TYO : 4503 | 10.14 [232] | 10.87 [233] | 10.08 [234] | 10.85 [235] | 11.29 [235] | 12.27 [236] | 12.07 | 12.63 | 11.48 |
Pharmaceutical Research and Manufacturers of America, formerly known as the Pharmaceutical Manufacturers Association, is an American trade group representing companies in the pharmaceutical industry. Founded in 1958, PhRMA lobbies on behalf of pharmaceutical companies. PhRMA is headquartered in Washington, D.C.
An epinephrine autoinjector is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It is most often used for the treatment of anaphylaxis. The first epinephrine autoinjector was brought to market in 1983.
Sanofi S.A. is a French multinational pharmaceutical and healthcare company headquartered in Paris, France. The corporation was established in 1973 and merged with Synthélabo in 1999 to form Sanofi-Synthélabo. In 2004, Sanofi-Synthélabo merged with Aventis and renamed to Sanofi-Aventis, which were each the product of several previous mergers. It changed its name back to Sanofi in May 2011. The company is a component of the Euro Stoxx 50 stock market index. In 2023, the company’s seat in Forbes Global 2000 was 89.
Judith Carol Lewent is a business executive who served as chief financial officer of Merck & Co. from 1990 until her retirement from the company in 2007. Since her retirement from Merck, she has continued to serve on multiple corporate boards, including the boards of GlaxoSmithKline, Thermo Fisher Scientific and Motorola Solutions. She also served on the board of Purdue Pharma until her departure from the company in 2014.
Elias Zerhouni is an Algerian-born American scientist, radiologist, biomedical engineer, entrepreneur, and pharmaceutical industry executive, known for having been the 15th Director of the National Institutes of Health.
Genome Valley is an Indian high-technology business district spread across 2,000-acre (8.1 km2)/(3.1 sq mi) in Hyderabad, India. It is located across the suburbs, Turakapally, Shamirpet, Medchal, Uppal, Patancheru, Jeedimetla, Gachibowli and Keesara. The Genome Valley has developed as a cluster for Biomedical research, training and manufacturing. Genome Valley is now into its Phase III, which is about 11 kms from the Phase I and II with the total area approximately 2,000-acre (8.1 km2).
The American Society of Hematology (ASH) is a professional organization representing hematologists, founded in 1958. Its annual meeting is held in December of every year and has attracted more than 30,000 attendees. The society publishes the medical journal Blood, the most cited peer-reviewed publication in the field, and Blood Advances, an online, peer-reviewed open-access journal.
The National Health Council (NHC) is a nonprofit association of health organizations.
The AIM at Melanoma Foundation(AIM) is a nonprofit organization focused on melanoma research.
The Reagan-Udall Foundation for the Food and Drug Administration is a private nonprofit (501c3) organization, created to support the mission of the U.S. Food and Drug Administration (FDA) to help equip FDA staff with the highest caliber, regulatory science and technology in order to enhance the safety and effectiveness of FDA regulated products. Although it was mandated by Congress in the Food and Drug Administration Amendments Act of 2007 to help support and promote FDA's regulatory science priorities, it is independent of the agency, with its own Board of Directors, staff and research agenda. The Reagan-Udall Foundation creates public–private partnerships to advance research in regulatory science, enhance medical decision making, and promote innovation. It also advances regulatory science through fellowships and other training programs, both for private scientists and for FDA staff.
The pharmaceutical industry in Pakistan was estimated to be worth Rs. 748 billion (US$2.6 billion) in 2023, representing about 1% of the country's GDP. The industry is largely import-dependent, with more than 90% of raw material being imported and only 12% of active pharmaceutical ingredients locally produced. Pakistani pharmaceutical companies are engaged in importing raw materials, compounding active pharmaceutical ingredients with excipients, coating of pills, and fill-finish activities. The industry is regulated by the Drug Regulatory Authority of Pakistan, which oversees drug approvals and pricing.
Alirocumab, sold under the brand name Praluent, is a medication used as a second-line treatment for high cholesterol for adults whose cholesterol is not controlled by diet and statin treatment. It is a human monoclonal antibody that belongs to a novel class of anti-cholesterol drugs, known as PCSK9 inhibitors, and it was the first such agent to receive FDA approval. The FDA approval was contingent on the completion of further clinical trials to better determine efficacy and safety.
Evolocumab, sold under the brand name Repatha, is a monoclonal antibody that is an immunotherapy medication for the treatment of hyperlipidemia.
The Sanofi–GSK COVID-19 vaccine, sold under the brand name VidPrevtyn Beta, is a COVID-19 vaccine developed by Sanofi Pasteur and GSK.
The Pharmaceutical Advertising Advisory Board (PAAB) is a Canadian not-for-profit organization based in Pickering, Ontario. Acting as a pseudo-regulatory body, PAAB offers review and pre-clearance services recognized by Health Canada to pharmaceutical companies and marketing agencies who wish to advertise directly to consumers and/or healthcare professionals. It is financed on a fee-for-service basis.
BIOTECanada, previously the Industrial Biotechnology Association of Canada, is a Canadian biotechnology industry association based in Ottawa, Ontario. It is an industry-funded membership organization composed of over 250 national and international pharmaceutical and gene therapy companies, medical device manufacturers, agricultural science businesses, law firms, academic institutions, research and development networks, advertising agencies, insurance companies and financial services firms.
{{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link)