Moroxydine

Last updated
Moroxydine
Moroxydine.png
Names
IUPAC name
N-(Diaminomethylidene)morpholine-4-carboximidamide
Other names
Moroxidine
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.020.994 OOjs UI icon edit-ltr-progressive.svg
EC Number
  • 223-093-1
KEGG
PubChem CID
UNII
  • InChI=1S/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10) X mark.svgN
    Key: KJHOZAZQWVKILO-UHFFFAOYSA-N X mark.svgN
  • InChI=1/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10)
    Key: KJHOZAZQWVKILO-UHFFFAOYAH
  • C1COCCN1C(=N)N=C(N)N
Properties
C6H13N5O
Molar mass 171.20 g/mol
Pharmacology
J05AX01 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Moroxydine is an antiviral drug that was originally developed in the 1950s as an influenza treatment. It has potential applications against a number of RNA and DNA viruses. [1] Structurally moroxydine is a heterocyclic biguanidine.[ citation needed ]

It was reported in March 2014 that three kindergartens in two provinces of China had been found to be secretly dosing their students with moroxydine hydrochloride to try to prevent them from becoming ill. The kindergartens are paid only for the days that pupils attend and wanted to ensure that they maximised their earnings. [2] In 2019, the Food and Drug Administration discovered the presence of moroxydine in an male enhancement product that was already found to contain undeclared sildenafil. [3]

References

  1. Sheppard, S. (1994). "Moroxydine: The story of a mislaid antiviral". Acta Dermato-Venereologica. Supplementum. 183: 1–9. PMID   9868507.
  2. Moore, Malcolm (2014-03-20). "China: All children to be given drug tests after schools caught medicating pupils". The Age. Retrieved 2014-03-20.
  3. "Public Notification: Black King Kong contains hidden drug ingredient". FDA. January 10, 2019.