N-acetylglucosamine kinase

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N-acetylglucosamine kinase
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N-acetylglucosamine kinase dimer, Thermotoga maritima
Identifiers
EC no. 2.7.1.59
CAS no. 9027-48-9
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MetaCyc metabolic pathway
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In enzymology, a N-acetylglucosamine kinase (EC 2.7.1.59) is an enzyme that catalyzes the chemical reaction

ATP + N-acetyl-D-glucosamine ADP + N-acetyl-D-glucosamine 6-phosphate

Thus, the two substrates of this enzyme are ATP and N-acetyl-D-glucosamine, whereas its two products are ADP and N-acetyl-D-glucosamine 6-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:N-acetyl-D-glucosamine 6-phosphotransferase. Other names in common use include acetylglucosamine kinase (phosphorylating), ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase, 2-acetylamino-2-deoxy-D-glucose kinase, and acetylaminodeoxyglucokinase. This enzyme participates in glutamate metabolism and aminosugars metabolism.

Related Research Articles

<span class="mw-page-title-main">Glycolysis</span> Series of interconnected biochemical reactions

Glycolysis is the metabolic pathway that converts glucose into pyruvate and, in most organisms, occurs in the liquid part of cells. The free energy released in this process is used to form the high-energy molecules adenosine triphosphate (ATP) and reduced nicotinamide adenine dinucleotide (NADH). Glycolysis is a sequence of ten reactions catalyzed by enzymes.

<span class="mw-page-title-main">Uridine triphosphate</span> Chemical compound

Uridine-5′-triphosphate (UTP) is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1′ carbon of the ribose sugar, and esterified with tri-phosphoric acid at the 5′ position. Its main role is as substrate for the synthesis of RNA during transcription. UTP is the precursor for the production of CTP via CTP synthetase. UTP can be biosynthesized from UDP by Nucleoside Diphosphate Kinase after using the phosphate group from ATP. UDP + ATP ⇌ UTP + ADP; both UTP and ATP are energetically equal.

In enzymology, an UDP-N-acetylglucosamine 6-dehydrogenase (EC 1.1.1.136) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Phosphoacetylglucosamine mutase</span>

In enzymology, a phosphoacetylglucosamine mutase is an enzyme that catalyzes the chemical reaction

The enzyme 2-dehydro-3-deoxy-6-phosphogalactonate aldolase catalyzes the chemical reaction

<span class="mw-page-title-main">Glucarate dehydratase</span>

The enzyme glucarate dehydratase (EC 4.2.1.40) catalyzes the chemical reaction

<span class="mw-page-title-main">Glucosamine-phosphate N-acetyltransferase</span>

In enzymology, glucosamine-phosphate N-acetyltransferase (GNA) is an enzyme that catalyzes the transfer of an acetyl group from acetyl-CoA to the primary amine in glucosamide-6-phosphate, generating a free CoA and N-acetyl-D-glucosamine-6-phosphate.

<span class="mw-page-title-main">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</span> Class of enzymes

In enzymology, an UDP-N-acetylglucosamine 1-carboxyvinyltransferase is an enzyme that catalyzes the first committed step in peptidoglycan biosynthesis of bacteria:

In enzymology, a poly(ribitol-phosphate) N-acetylglucosaminyl-transferase is an enzyme that catalyzes the chemical reaction

In enzymology, a 2-dehydro-3-deoxygalactonokinase is an enzyme that catalyzes the chemical reaction

In enzymology, an acetylglutamate kinase is an enzyme that catalyzes the chemical reaction:

In enzymology, a dephospho-CoA kinase is an enzyme that catalyzes the chemical reaction

In enzymology, a glucosamine kinase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">N-acylmannosamine kinase</span>

In enzymology, a N-acylmannosamine kinase is an enzyme that catalyzes the chemical reaction

In enzymology, an UDP-galactose—UDP-N-acetylglucosamine galactose phosphotransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a phosphoribokinase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">UDP-glucose—hexose-1-phosphate uridylyltransferase</span> Class of enzymes

In enzymology, an UDP-glucose—hexose-1-phosphate uridylyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">UDP-N-acetylglucosamine diphosphorylase</span> Class of enzymes

In enzymology, an UDP-N-acetylglucosamine diphosphorylase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Xylulokinase</span>

In enzymology, a xylulokinase is an enzyme that catalyzes the chemical reaction

UDP-N-acetylglucosamine kinase is an enzyme with systematic name ATP:UDP-N-acetyl-alpha-D-glucosamine 3'-phosphotransferase. This enzyme catalyses the following chemical reaction

References