Pantoate kinase

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Pantoate kinase
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EC no. 2.7.1.169
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Pantoate kinase (EC 2.7.1.169, PoK, TK2141 protein) is an enzyme with systematic name ATP:(R)-pantoate 4-phosphotransferase. [1] This enzyme catalyses the following chemical reaction

ATP + (R)-pantoate ADP + (R)-4-phosphopantoate

The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is done during biosynthesis of 4'-phosphopantetheine,.

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References

  1. Yokooji Y, Tomita H, Atomi H, Imanaka T (October 2009). "Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea". The Journal of Biological Chemistry. 284 (41): 28137–45. doi: 10.1074/jbc.m109.009696 . PMC   2788864 . PMID   19666462.