Propionate kinase

Last updated
Propionate kinase
Identifiers
EC no. 2.7.2.15
CAS no. 39369-28-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

Propionate kinase (EC 2.7.2.15, PduW, TdcD, propionate/acetate kinase) is an enzyme with systematic name ATP:propanoate phosphotransferase. [1] [2] [3] [4] [5] [6] This enzyme catalyses the following chemical reaction

ATP + propanoate ADP + propanoyl phosphate

This enzyme requires Mg2+.

References

  1. ↑ Hesslinger C, Fairhurst SA, Sawers G (January 1998). "Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate". Molecular Microbiology. 27 (2): 477–92. doi:10.1046/j.1365-2958.1998.00696.x. PMID   9484901.
  2. ↑ Palacios S, Starai VJ, Escalante-Semerena JC (May 2003). "Propionyl coenzyme A is a common intermediate in the 1,2-propanediol and propionate catabolic pathways needed for expression of the prpBCDE operon during growth of Salmonella enterica on 1,2-propanediol". Journal of Bacteriology. 185 (9): 2802–10. doi:10.1128/jb.185.9.2802-2810.2003. PMC   154405 . PMID   12700259.
  3. ↑ Wei Y, Miller CG (October 1999). "Characterization of a group of anaerobically induced, fnr-dependent genes of Salmonella typhimurium". Journal of Bacteriology. 181 (19): 6092–7. doi:10.1128/JB.181.19.6092-6097.1999. PMC   103637 . PMID   10498722.
  4. ↑ Ingram-Smith C, Gorrell A, Lawrence SH, Iyer P, Smith K, Ferry JG (April 2005). "Characterization of the acetate binding pocket in the Methanosarcina thermophila acetate kinase". Journal of Bacteriology. 187 (7): 2386–94. doi:10.1128/jb.187.7.2386-2394.2005. PMC   1065240 . PMID   15774882.
  5. ↑ Simanshu DK, Murthy MR (January 2005). "Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of propionate kinase (TdcD) from Salmonella typhimurium". Acta Crystallographica Section F. 61 (Pt 1): 52–5. doi:10.1107/s1744309104026429. PMC   1952409 . PMID   16508089.
  6. ↑ Simanshu DK, Savithri HS, Murthy MR (September 2005). "Crystal structures of ADP and AMPPNP-bound propionate kinase (TdcD) from Salmonella typhimurium: comparison with members of acetate and sugar kinase/heat shock cognate 70/actin superfamily". Journal of Molecular Biology. 352 (4): 876–92. doi:10.1016/j.jmb.2005.07.069. PMID   16139298.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.