Pseudaminic acid cytidylyltransferase

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Pseudaminic acid cytidylyltransferase
Identifiers
EC no. 2.7.7.81
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MetaCyc metabolic pathway
PRIAM profile
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NCBI proteins

Pseudaminic acid cytidylyltransferase (EC 2.7.7.81, PseF) is an enzyme with systematic name CTP:5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-nonulosonic acid cytidylyltransferase. [1] This enzyme catalyses the following chemical reaction

CTP + 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid diphosphate + CMP-5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid

Mg2+ is required for activity.

References

  1. Schoenhofen IC, McNally DJ, Brisson JR, Logan SM (September 2006). "Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction". Glycobiology. 16 (9): 8C –14C. doi: 10.1093/glycob/cwl010 . PMID   16751642.