Cockade sign

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The cockade sign is a radiological feature associated with intraosseous lipoma, a rare benign tumor of the bone composed primarily of mature adipose tissue. [1] [2] This sign describes the characteristic appearance of a central calcification or ossification surrounded by radiolucent fatty tissue on imaging, resembling a bullseye or cockade. [3]

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Pathogenesis

Intraosseous lipomas are thought to arise from the proliferation of adipose tissue within the medullary cavity of bone. Over time, ischemic changes within the lesion may lead to necrosis, calcification, or cystic transformation. These secondary changes are responsible for the imaging characteristics, including the cockade sign. The cockade sign develops due to central calcification or ossification. The radiolucent fatty component forms the outer ring of the lesion. [4]

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References

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  3. Team, radRounds (22 July 2020). "Cockade Sign". radRounds Radiology Network. Retrieved 2 January 2025.
  4. Campbell, R. S. D.; Grainger, A. J.; Mangham, D. C.; Beggs, I.; Teh, J.; Davies, A. M. (1 April 2003). "Intraosseous lipoma: report of 35 new cases and a review of the literature". Skeletal Radiology. 32 (4): 209–222. doi:10.1007/s00256-002-0616-7. ISSN   1432-2161 . Retrieved 2 January 2025.
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