flavone apiosyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.2.25 | ||||||||
CAS no. | 37332-49-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a flavone apiosyltransferase (EC 2.4.2.25) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are UDP-apiose and 5,7,4'-trihydroxyflavone 7-O-beta-D-glucoside, whereas its 3 products are UDP, 5,7,4'-trihydroxyflavone (apigenin), and [[7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]]].
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase. Other names in common use include uridine diphosphoapiose-flavone apiosyltransferase, and UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase. This enzyme participates in flavonoid biosynthesis.
Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool.
Flavonoids are synthesized by the phenylpropanoid metabolic pathway in which the amino acid phenylalanine is used to produce 4-coumaroyl-CoA. This can be combined with malonyl-CoA to yield the true backbone of flavonoids, a group of compounds called chalcones, which contain two phenyl rings. Conjugate ring-closure of chalcones results in the familiar form of flavonoids, the three-ringed structure of a flavone. The metabolic pathway continues through a series of enzymatic modifications to yield flavanones → dihydroflavonols → anthocyanins. Along this pathway, many products can be formed, including the flavonols, flavan-3-ols, proanthocyanidins (tannins) and a host of other various polyphenolics.
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The molecular formula C21H20O10 (molar mass: 432.38 g/mol, exact mass: 432.105647 u) may refer to:
Apiose is a branched-chain sugar found as residues in galacturonans-type pectins; that occurs in parsley and many other plants. Apiose is a component of cell wall polysaccharides.
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