GDP-D-glucose phosphorylase

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GDP-D-glucose phosphorylase
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EC no. 2.7.7.78
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GDP-D-glucose phosphorylase (EC 2.7.7.78) is an enzyme with systematic name GDP:alpha-D-glucose 1-phosphate guanylyltransferase. [1] This enzyme catalyses the following chemical reaction

GDP-alpha-D-glucose + phosphate alpha-D-glucose 1-phosphate + GDP

The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates.

Related Research Articles

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References

  1. Adler LN, Gomez TA, Clarke SG, Linster CL (June 2011). "A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals". The Journal of Biological Chemistry. 286 (24): 21511–23. doi: 10.1074/jbc.m111.238774 . PMC   3122210 . PMID   21507950.