Isopentenyl phosphate kinase

Isopentenyl phosphate kinase
Identifiers
EC no.	2.7.4.26
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Isopentenyl phosphate kinase (EC 2.7.4.26) is an enzyme with systematic name ATP:isopentenyl phosphate phosphotransferase. ^{[1] [2] [3] [4]} This enzyme catalyses the following chemical reaction

ATP + isopentenyl phosphate ${\displaystyle \rightleftharpoons }$ ADP + isopentenyl diphosphate

This enzyme takes part in the mevalonate pathway in Archaea.

References

1. Grochowski LL, Xu H, White RH (May 2006). "Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate". Journal of Bacteriology. 188 (9): 3192–8. doi:10.1128/JB.188.9.3192-3198.2006. PMC   1447442 . PMID   16621811.
2. Lange BM, Croteau R (November 1999). "Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step". Proceedings of the National Academy of Sciences of the United States of America. 96 (24): 13714–9. Bibcode:1999PNAS...9613714L. doi: 10.1073/pnas.96.24.13714 . PMC   24130 . PMID   10570138.
3. Chen M, Poulter CD (January 2010). "Characterization of thermophilic archaeal isopentenyl phosphate kinases". Biochemistry. 49 (1): 207–17. doi:10.1021/bi9017957. PMC   3856865 . PMID   19928876.
4. Mabanglo MF, Schubert HL, Chen M, Hill CP, Poulter CD (May 2010). "X-ray structures of isopentenyl phosphate kinase". ACS Chemical Biology. 5 (5): 517–27. doi:10.1021/cb100032g. PMC   2879073 . PMID   20402538.

External links

• Isopentenyl+phosphate+kinase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)