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This is a list of notable people who are reported to have died from coronavirus disease 2019 (COVID-19) in South Africa, as a result of infection by the virus SARS-CoV-2 during the COVID-19 pandemic.
|Date||Name||Sex||Age||Notability||Place of death||Ref.|
|31 March 2020||Gita Ramjee||F||63||Scientist and researcher in HIV prevention.||KwaZulu-Natal, Umhlanga|
|12 May 2020||Clarence Mini||M||68||Chairperson of the Council of Medical Schemes, uMkhonto we Sizwe, AIDS activist||Gauteng, Johannesburg|
|13 May 2020||Dorah Dunana Dlamini||F||57||Member of the National Assembly|
|14 June 2020||Elsa Joubert||F||97||Author||Western Cape, Cape Town|
|28 June 2020||Gordon Kegakilwe||M||53||North West MEC for Cooperative Governance, Human Settlement and Traditional Affairs||Gauteng, Klerksdorp|
|7 July 2020||Henry Jansen||M||64||Mayor of Langeberg||Western Cape, Worcester|
|8 July 2020||Ricardo Mthembu||M||50||Member of the KwaZulu-Natal Legislature and ANC provincial spokesperson||KwaZulu-Natal, KwaDukuza|
|8 July 2020||Queen Noloyiso Sandile||F||57||Regent of the AmaRharhabe||Eastern Cape, Mdantsane|
|10 July 2020||Corra Dirksen||M||82||Springboks rugby player||Gauteng, Klerksdorp|
|10 July 2020||Thomas Manthata||M||80||Anti-Apartheid activist (Delmas Treason Trial)||Gauteng, Thaba Tshwane|
|12 July 2020||Alfred Mtsi||M||70||Mayor of Buffalo City (2015–2016)||Eastern Cape, East London|
|13 July 2020||Zindzi Mandela||F||59||Daughter of Nelson Mandela.||Gauteng, Johannesburg|
|18 July 2020||Martha Mmola||F||Delegate of the National Council of Provinces|
|19 July 2020||Zamuxolo Peter||M||55||Member of the National Assembly of South Africa|
|7 August 2020||Lungile Pepeta||M||46||Paediatric cardiologist. Dean of health sciences at Nelson Mandela University.||Eastern Cape, Port Elizabeth|
|12 August 2020||Mac Jack||M||55||Northern Cape MEC for Education.||Northern Cape, Kimberley|
|18 August 2020||Mongameli Bobani||M||52||Former Mayor of the Nelson Mandela Bay Metropolitan Municipality||Eastern Cape, Port Elizabeth|
|22 November 2020||Mncedisi Filtane||M||73||Member of the Eastern Cape Provincial Legislature|
|7 December 2020||Dawn Lindberg||F||75||Entertainer||Western Cape, Plettenberg Bay|
|7 December 2020||Pumza Dyantyi||F||72||Eastern Cape MEC for Social Development||Eastern Cape Province|
|9 December 2020||Gordon Forbes||M||86||Tennis player||Western Cape, Plettenberg Bay|
|13 December 2020||Ambrose Mandvulo Dlamini||M||52||Prime Minister of Eswatini||Gauteng, Milpark|
|25 December 2020||Robin Jackman||M||75||Cricketer and radio/TV commentator||Western Cape, Cape Town|
|25 December 2020||Patrick Bayo Mkhize||M||60||Black Consciousness Movement, general secretary of the Transport Retail and General Workers’ Union||KwaZulu-Natal, Durban|
|26 December 2020||Aubrey Mokoape||M||76||Anti-apartheid activist||KwaZulu-Natal, Durban|
|26 December 2020||Nomvuzo Shabalala||F||60||Member of the National Assembly|
|5 January 2021||Mluleki George||M||72||Politician, sports administrator||Eastern Cape, East London|
|9 January 2021||Johnson Mlambo||M||81||Politician||Gauteng, Johannesburg|
|13 January 2021||Bheki Ntuli||M||63||KwaZulu-Natal MEC for Transport, Community Safety & Liaison||KwaZulu-Natal, Durban|
|17 January 2021||Abel Gabuza||M||65||Archbishop Coadjutor of the Archdiocese of Durban||KwaZulu-Natal, Durban|
|17 January 2021||Marius Swart||M||79||Executive Mayor of the George Local Municipality and Member of the National Assembly of South Africa||Western Cape, George|
|18 January 2021||Nombulelo Hermans||F||51||Member of the National Assembly of South Africa|
|21 January 2021||Jackson Mthembu||M||62||Minister in the Presidency of South Africa's government, and parliamentarian for the African National Congress (ANC)||Gauteng, Johannesburg|
|22 January 2021||Marius van Heerden||M||46||Former SA 800 metres record holder and Olympian||Western Cape, Cape Town|
|28 January 2021||Kenneth Mthiyane||M||76||Justice of the Supreme Court of Appeal of South Africa||Western Cape, Cape Town|
|29 January 2021||Percy Tucker||M||92||Ticket booking agent, launched the world's first computerized theatre reservation system in 1971||Western Cape, Cape Town|
|31 January 2021||Tozama Mantashe||F||60||Member of the National Assembly of South Africa (since 2014)|
|4 February 2021||Zwelifile Christopher Ntuli||M||Member of the KwaZulu-Natal Legislature and member of the National Assembly of South Africa|
|4 March 2021||Karima Brown||F||54||Senior South African journalist||Gauteng, Johannesburg|
|12 March 2021||Goodwill Zwelethini kaBhekuzulu||M||72||The King of the Zulu nation||KwaZulu-Natal, Durban|
|4 April 2021||Frank Mdlalose||M||89||Political activist and the first Premier of KwaZulu-Natal||KwaZulu-Natal, Durban|
|10 April 2021||Sindisiwe van Zyl||F||45||Former Kaya FM presenter, medical doctor and life coach||Gauteng, Johannesburg|
|22 April 2021||Jacqueline Mofokeng||F||61||South African politician, African National Congress member in the Gauteng Provincial Legislature||Gauteng, Johannesburg|
|19 May 2021||Tshoganetso Tongwane||F||65||Member of the National Assembly of South Africa|
|26 May 2021||Ben Kruger||M||64||Actor, author||Gauteng, Pretoria|
|11 June 2021||Taha Karaan||M||52||Islamic scholar||Western Cape, Cape Town|
|15 June 2021||James Jim Skosana||M||59||Member of the Mpumalanga Provincial Legislature, member of the National Assembly of South Africa|
|16 June 2021||Jabu Mabuza||M||63||Businessperson and investor|
|29 June 2021||Goolam Rajah||M||74||Manager of the South Africa national cricket team, pharmacist||Gauteng, Johannesburg|
|30 June 2021||Richard Dolley||M||61||Cricketer, educator, and hockey administrator|
|1 July 2021||Steve Kekana||M||62||Singer and songwriter|
|2 July 2021||Lehlo Ledwaba||M||49||Boxer||Gauteng, Johannesburg|
|3 July 2021||Diratsagae Alfred Kganare||M||Member of the National Assembly of South Africa||Gauteng, Johannesburg|
|7 July 2021||Cameron Mackenzie||M||60||Member of the National Assembly of South Africa||Gauteng, Johannesburg|
|9 July 2021||Geoff Makhubo||M||53||Mayor of Johannesburg||Gauteng, Johannesburg|
|July 2021||Lesego Semenya||M||39||Celebrity chef|
|12 July 2021||Ben Ngubane||M||79||Ambassador to Japan, Minister of Arts and Culture, Premier of KwaZulu-Natal and member of the National Assembly of South Africa||KwaZulu-Natal, Richards Bay|
|16 July 2021||Joyce Maluleke||F||60||Member of the National Assembly of South Africa (since 2015)|
|21 July 2021||Lieb Bester||M||72||Actor||Gauteng, Pretoria|
|22 July 2021||Andre Thysse||M||52||Boxer, boxing promoter|
|22 July 2021||Ian Palmer||M||55||Soccer player, coach|
|23 July 2021||Lulama Ntshayisa||M||62||Member of the National Assembly of South Africa (since 2014)|
|30 July 2021||Shona Ferguson||M||47||Actor and producer||Gauteng, Johannesburg|
|31 July 2021||Jacobus Frederick van Wyk||M||69||Member of the Northern Cape Provincial Legislature (2004–2013) and Member of the National Assembly of South Africa (1997–2004)||Northern Cape, Steinkopf|
|23 August 2021||Giovanni Pretorius||M||49||Olympic boxer|
|3 September 2021||John Watkins||M||98||Cricketer||KwaZulu-Natal, Durban|
|6 September 2021||Zanele kaMagwaza-Msibi||F||59||Politician, leader of the National Freedom Party||KwaZulu-Natal, Durban|
|11 October 2021||Ockert Potgieter||M||55||Missionary in the Ukraine, Film Director||Mossel Bay South Africa|
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