COVID-19 vaccination in South Africa

Last updated

COVID-19 vaccination in South Africa
Covid-19 vaccination in South Africa (Total Dose).svg
Total doses administered as of 20 July 2021
Native name Sisonke Protocol (Phase III J&J)
Date17 February 2021 - present
Time(SAST (GMT +2))
Venue1397 vaccination clinics [1]
3,338 (Planned) [2]
Location South Africa
Cause COVID-19 pandemic
BudgetR10 billion (Distribution 2021)
R2.2 billion (Q1 2021 purchasing vaccines)
R1.25 billion (Q2 2021 purchasing vaccines)
TBA (Q3 2021 purchasing vaccines)
USD $1,000,000,000 [3] [4] [5]
Organised by Department of Health (South Africa) & Government of South Africa
Participants20,381,262 total doses administered of
Janssen
Pfizer–BioNTech
(27 August 2021)
  • 14,197,617 people with only 1 dose of multiple dose vaccine
  • 10,891,293 people fully vaccinated
Outcome
  • 36% of the South African adult population with at least 1 dose
    36%
  • 27% of the South African adult population that is fully vaccinated.
    27%
Website Vaccine Enrollment Platform

COVID-19 vaccination in South Africa is an ongoing immunisation campaign against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), in response to the ongoing pandemic in the country.

Contents

Fully vaccinated people as of 20 July 2021 Covid-19 vaccination in South Africa (Fully vaccinated).svg
Fully vaccinated people as of 20 July 2021

On 17 February 2021, South Africa started its national vaccination program against Covid-19. The program will go through in phases, prioritizing healthcare and frontline workers and then those over the age of 60. According to health officials, South Africa has administered 24 082 686 vaccine doses across the country as of 15 November 2021. [6] [7] South Africa has accepted delivery of 3 different vaccines, Johnson and Johnson, Pfizer-BioNTech and Oxford-AstraZeneca, administering both Janssen (Johnson & Johnson) and Pfizer-BioNTech, with the Oxford-AstraZeneca vaccine suspended, due to its ineffectiveness against the Beta variant (501.V2). [8]

Total number of people receiving vaccinations in South Africa as of 27 Aug 2021

  Unvaccinated population: 50,973,612 people (with estimated total population of 60 million) (84.95%)
  Population who are partially vaccinated (only one dose of multi-dose vaccine): 3,424,542 (5.71%)
  Population who are fully Vaccinated: 5,601,878 (9.34%)

Background

Rollout strategy

National Vaccine Rollout Strategy
PhasePriority groupStart datePeople
eligible [9]
ProgressPeople Vaccinated
(2021-11-20) [10]
Phase 1
1aFront-line and health care workers (Sisonke Protocol) [11] [12] 17 Feb 2021 [10] 497679Complete497679
1bRemaining health care workers [13] 17 May 2021700000In progress [lower-alpha 1] [14] 320066
Phase 2
Age Based Prioritisation
2aiPeople over 60 [13] 17 May 20215000000In progress3 516 775
2aiiPeople 50-59 [15] 5 July 20214800000In progress2796463
2aiiPeople 35-49 [16] 15 July 202111000000In progress5258886
Employment Based Prioritisation [17]
2biTeachers and support staff [18] 23 June 2021582000CompleteTBA
2biiPolice Force, SANDF, inmates & prison staff [19] 5 July 2021800000CompleteTBA
2biiiFrontline social workers [20] 19 July 2021240000CompleteTBA
2bivMedia workers and journalists [21] 30 July 2021TBACompleteTBA
Phase 3
3People 18-34 [22] 20 Aug 202117900000In progress4638613
Phase 4
4aKids and teenagers 12-17 [23] 20 Oct 20216 500 000In progress345035
4bBoosters for Sisonke Trial participants [24] 10 Nov 2021 [25] [10] 497679In progress [26] 81 609
Phase 5
5Undocumented Migrants [27] TBATBANot startedN/A

Registration

As of 20 October 2021, registration for the Covid-19 vaccine has been opened to people aged 12 and older. [22] There are currently 5 ways to register for the vaccine, including online on the EVDS platform. All services are zero rated, meaning airtime, data or money are not required to use the service. [28] [29]

Vaccines on order

South Africa has ordered 60 million doses of vaccines, received 52.6 million doses in donations and expects a total of 9 million doses from Covax, with 320 million doses of the Johnson & Johnson and Pfizer vaccines to be manufactured locally for international and local distribution. [30] [31] South Africa has accepted delivery of 11,059,420 doses of vaccines, with 1.5 million doses cleared after local manufacturing.

Vaccine nameApproval progressQuantityDoses arrivedAccepted deliverySection 21 (EUA)Began administeringFull Approval
Oxford–AstraZeneca EUA Suspended1.5 Million1,000,000Green check.svg 1 February 2021Dark Red x.svg SuspendedDark Red x.svg SuspendedN/A
Janssen vaccine EUA Approved30 Million6,401,600Green check.svg 16 February 2021Green check.svg 1 April 2021 (full authorization)Green check.svg 18 Feb 2021 (Phase III)Pending
Pfizer vaccine EUA Approved30 Million [32] 11,274,120Green check.svg 3 May 2021Green check.svg 16 March 2021Green check.svg 17 May 2021Pending
CoronaVac Vaccine EUA Approved0 [33] 0Dark Red x.svg Not yetGreen check.svg 3 July 2021Dark Red x.svg Not yetN/A
COVAX
Pfizer vaccine EUA Approved1.4 Million1,400,000Green check.svg 27 June 2021Green check.svg 16 March 2021Green check.svg 17 May 2021Pending
Other (TBA)EUA pending7.6 Million0Dark Red x.svg Not yetDark Red x.svg Not yetDark Red x.svg Not yetN/A
Donations
United States of America
Pfizer Vaccine EUA Approved7.86 Million7.86 MillionTBATBATBAPending
Local Manufacturing
Janssen vaccine EUA Approved220 Million32 MillionGreen check.svg 16 February 2021Green check.svg 1 April 2021 (full authorization)Green check.svg 18 Feb 2021 (Phase III)Pending
Pfizer vaccine EUA Approved100 Million0TBATBATBAPending

Vaccine Consignments

Johnson & Johnson consignment (Phase III/Sisonke Protocol)

Consignment 1
180000 doses17 February 2021Fully used
Consignment 2
280000 doses27 February 2021Fully used
Consignment 3
3a86000 doses7 March 2021Fully used
3b40000 doses13 March 2021Fully used
3c66000 doses20 March 2021Fully used
Consignment 4
4200000 doses11 April 2021Used, remainder doses allocated for further studies

Johnson & Johnson Consignment (Section 21/EUA Approval)

Consignment 1 (manufactured locally)
11099200 dosesAprilManufactured (destroyed due to contamination)
2900000 dosesMayManufactured (destroyed due to contamination)
−199920013 JuneStock will not be used due to ingredients being contaminated [34]
Emergency Consignment (make up for contaminated doses) [35]
1300000 doses18 June [36] Fully used
21253600 doses24 JuneFully used [37] [38]
Consignment 2 [39]
11 454 400 doses26 JulyIn Use [40] [41] [42] [43]
2619 200 doses9 AugIn Use [44] [45]
31 413 600 doses6 SeptDelivered [46]
41 360 800 doses13 SeptDelivered [46]
5TBASept 2021TBA [47]
Consignment 3
119100000 dosesQ4 2021 [48] TBA

Oxford-AstraZeneca Consignment

Consignment 1 [49]
1a1000000 doses1 February 2021Received
1b500000 doses14 February 2021Canceled and refunded
1c−1000000 doses20 February 20211,000,000 doses sold

Pfizer-BioNTech Consignment

Consignment 1
1325260 doses3 May 2021Fully used
2325260 doses10 May 2021Fully used
3325260 doses16 May 2021Fully used
4325260 doses24 May 2021Fully used
Consignment 2
1636480 doses31 May 2021Fully used
2636480 doses7 June 2021Fully used
3636480 doses14 June 2021Fully used
4636480 doses21 June 2021Fully used
5636480 doses28 June 2021Fully used
Consignment 3 [48] [50] [15] [37] [51] [52]
1190 710 doses7 July 2021Fully used
2288 990 doses12 July 2021Fully used
3673 920 doses19 July 2021Fully used
4968 760 doses26 July 2021Fully used
Consignment 4 [53] [54] [43] [55] [39] [47]
11 556 100 doses2 Aug 2021Fully used
21 556 100 doses9 Aug 2021Fully used
31 556 100 doses16 Aug 2021In use
41 556 100 doses23 Aug 2021In use
51 556 100 doses30 Aug 2021Delivered
61 556 100 doses6 Sept 2021Delivered
4 063 400 dosesTBA Sept 2021TBA
Consignment 5 [48] [54]
8997300 dosesQ4 2021TBA

CoronaVac Consignment

Not yet ordered. Waiting for evidence of efficacy against Delta variant and for those with HIV [56] [57] [52] [33]

Donations

United States Consignment 1 (Pfizer) [58] [59] [60] [43] [39]
12815020 doses31 July 2021In use
22845440 doses2 Aug 2021Delivered
United States Consignment 2 (Pfizer) [61] [62]
12 200 000 doses28 Aug 2021Delivered

COVAX

South Africa has so far paid R283 million ($20 million) to the organization in December 2020. COVAX has delivered 1.4 million doses of the Pfizer vaccine to the country on 28 June 2021. [63] [64]

Covax Consignment

Consignment 1 (Pfizer)
11392300 doses27 June 2021Fully used [37]
Consignment 2 (Pfizer)
11 181 706 dosesQ3 2021TBA [54]

History

Timeline

February 2021

Completed vaccinations per pharmaceutical company as of 14 August 2021 (4,074,588)

  Johnson & Johnson (2,081,229) (51.08%)
  Pfizer–BioNTech (1,993,359) (48.92%)

On 1 February 2021, 1 million doses of the Oxford AstraZeneca vaccine at O. R. Tambo International Airport sent by the Serum Institute of India. [65] [66] [67]

On 7 February 2021, it was announced that the Oxford–AstraZeneca COVID-19 vaccine did not work well in protecting clinical trial participants from mild or moderate illness caused by the 501.V2 variant. The vaccination program was announced to be put on a hold. [68] [69] [70]

On 16 February 2021, South Africa received its first consignment of 80,000 doses of the Janssen vaccine and approved the vaccine for Phase III use under Sisonke Protocol for all health workers [71]

On 17 February 2021, the national COVID vaccination program was officially rolled out, beginning at Khayelitsha District Hospital in the Western Cape Province where healthcare workers, the President Cyril Ramaphosa and Minister of Health Zweli Mkhize were given shots of the Janssen COVID-19 vaccine. [72] [73] [11]

On 27 February 2021, South Africa had received its second consignment of 80,000 doses of the Janssen vaccine. [74] [75]

March 2021

On 5 March 2021, the number of doses administered surpassed 100,000. [76]

On 13 March 2021, South Africa received Part 1 of its third consignment of 40,000 Janssen COVID-19 vaccine. [77] [78]

On 17 March 2021, South African Health Products Regulatory Authority (SAHPRA) approved the Pfizer/BioNTech coronavirus vaccine for use. [79] [80] [81] [82]

On 18 March 2021, South Africa received Part 2 of its third consignment of 66,000 Janssen vaccine. [83] [84]

On 19 March 2021, ImmunityBio announced that they will be conducting Phase 1 vaccine trials with their hAd5 vaccine in the United States and South Africa. [85] [86]

On 21 March 2021, South Africa sold and began transporting its 1 million doses of Oxford-AstraZeneca vaccine to other African Union Members. Concerns over the rollout of the vaccine in African countries have been raised, as the 501Y.V2 variant speeds through African countries, with South Africa Suspending the vaccine after a trial proved the vaccine to be ineffective. [87] [88] [89] [90] [49]

On 29 March 2020, the manufacturing of 220 million doses of the Janssen vaccine was approved to begin at the Aspen Pharmacare manufacturing facility in Port Elizabeth, Eastern Cape. [91] [92]

April 2021

On 1 April 2021, the Janssen vaccine received Section 21 Approval (EUA), allowing for use outside of the current Phase III Trial (Sisonke Protocol). [93] [94] [95]

On 6 April 2021, the government officially signed a deal with Pfizer for 20 million vaccines expected to begin arriving by the end of April. [96] [97]

On 13 April 2021, Minister of Health Zweli Mkhize announced the suspension of Janssen COVID-19 vaccine use following health concerns raised by the Food and Drug Administration (FDA). [98] [99] [100]

On 16 April 2021, The EVDS platform opened for Phase 2, allowing essential workers and the elderly to register. [101] [102] [103]

On 17 April 2021, the government announced that the first batch of 325,260 Doses of Pfizer vaccines would arrive on 3 May 2021. From there the same amount of doses are expected to arrive weekly, until 31 May 2021, where the number of daily doses delivered will increase to 636,480 weekly. [8]

On 23 April 2021, 500,000 Doses of the Janssen vaccine were delivered under the early access program (Sisonke Programme), with a further 1,000,000 million doses to arrive in April. [98] [104]

On 24 April 2021, Aspen Pharmacare announced that 1.1 million doses of the Janssen vaccine were due for release and to be used by South Africa. [105]

On 26 April 2021, the government announced that the use of the Janssen COVID-19 vaccine would resume on Wednesday, 28 April 2021 with vaccination sites expanded to 95 sites countrywide. [104]

On 28 April 2021, the Janssen vaccines suspension was lifted, and given the full approval for use by SAPRAH. [106] [107] [108]

May 2021

On 2 May 2021, the government announced that the first 1.1 million doses of the Janssen vaccine would receive an extended safety assessment, in line with international regulators, and stock would be released in mid May. [109]

On 3 May 2021, the first batch of 325,260 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport via Lufthansa and Astral Aviation. The vaccines were then sent to the National Control Laboratory for quality assurance. [110] [111] [112] [113] The Pfizer-BioNTech vaccine is set to be rolled out to South Africans from 17 May 2021. [114] [115]

On 9 May 2021, the second batch batch of 325,260 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport via Lufthansa and Astral Aviation. [116]

On 10 May 2021, the last week of the Sisonke Protocol (Phase 3b) began. The trial was expanded to non patient facing health care workers, including administrative and supportive staff due to sufficient capacity and doses. [117]

On 15 May 2021, the Sisonke Protocol ended with a total of 478 733 doses given to health care workers. The remaining doses were allocated to the Medical research Council to conduct further studies of the Johnson & Johnson vaccine on certain population groups. [116]

On 16 May 2021, the third batch of 325,260 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport via Lufthansa and Astral Aviation. [116]

On 17 May 2021, Phase 2 of the vaccination program began and started with vaccinating old age homes with the 2-dose Pfizer vaccine. Phase 2 ran alongside phase 1B to vaccinate the remaining 500 000 health care workers. [118]

On 24 May 2021, the fourth and final batch of 325,260 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport via Lufthansa and Astral Aviation. [116] Following this, next week doses delivered will increase to 636,480 Doses weekly. [119]

On 31 May 2021, the first batch of 636,480 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport via Lufthansa and Astral Aviation. This delivery is the first batch of consignment 2 with an incremental increase of 311,220 Doses Weekly. [120]

On 31 May 2021, the total number of vaccine doses administered surpassed 1 million. [121]

June 2021

On 7 June 2021, the second batch of 636,480 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport. [122]

On 11 June 2021, the Department of Health and Food and Drug Administration (FDA) released a statement on the Janssen vaccine, produced at the Emergent BioSolutions Plant in Baltimore, USA. [123] This resulted in the vaccines also produced at the Port Elizabeth plant need further assessment by SAHPRA and the FDA. [124] [125] To get the South African program back on the roll, 300 000 doses are cleared to be shipped to South Africa as a matter of extreme urgency. [126] [127]

On 14 June 2021, the third batch of 636,480 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport. [128]

On June 18, 2021, 300,000 doses of the Janssen vaccine arrived at O.R Tambo International Airport. This is the first batch of the Emergency consignment due to contamination of locally manufactured doses. These doses are expected to be used mainly by teachers and the SANDF and SAPS. [36] [129]

On 18 June 2021, the total number of vaccine doses administered surpassed 2 million. [130]

On 21 June 2021, the fourth batch of 636,480 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport. [131] [132]

On 25 June 2021, the second batch of 1,200,000 Doses of the Janssen vaccine arrived at O.R Tambo International Airport. [131] [132] [133]

On 28 June 2021, the fifth batch of 636,480 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport. [134] [135]

By the end of the month, 2.7 million vaccine doses had been administered. 2% of the target population had been fully vaccinated by the end of June.

July 2021

On 3 July 2021, SAHPRA approved China's Sinovac CoronaVac Vaccine for local use via emergency use authorisation on the condition that Sinovac provides further information on risk and efficacy. [136] [137] [138] [139]

On 5 July 2021, the Department of Health announced that the government would now reimburse private sites for the vaccinations of all uninsured people. Allowing any person qualified for a vaccine to be allocated to the most appropriate site, regardless if it is private or public. The rollout for the Police Force, South Africa National Defense Force, Inmates and Prison Staff commenced. [140]

On 7 July 2021, the 190,710 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport. [141]

During the 2021 South African unrest, the vaccine rollout encountered a slowdown as businesses and vaccine sites were shut down due to protests and looting in Gauteng and Kwazulu-Natal. [142] [143] [144]

On 12 July 2021, 288,990 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport. [56] [54] [53]

On 14 July 2021, the rollout for educators officially ended with more than 500 000 people being vaccinated. However, any educators who could not make it to a vaccination site during the official program still qualify to be vaccinated. [145]

On 15 July 2021, the rollout for Correctional Services officials began. [19]

On 19 July 2021, the rollout for 240 000 social development staff began. This program includes early childhood development (ECD) workforce, social service professionals, community development practitioners and frontline Department of Social Development staff. [20]

On 19 July 2021, 973,920 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport. [58]

On 20 July 2021, the rollout for inmates at 90 correctional centres began. [19]

On 21 July 2021, Pfizer and BioNTech signed a letter of intent with Cape Town based Biovac, committing to allow Biovac to 'fill and finish' 100 million doses of the Pfizer-BioNTech vaccine for use in the African Union. The first doses completed by Biovac will only be released in 2022. [146] [147] [148]

On 24 July 2021, the Janssen vaccine got incorporated into the general vaccine rollout, no longer only for essential worker programs, due to the close expiry date for the emergency consignment doses and confirmation that additional doses would soon arrive. [149]

On 25 July 2021, President Ramaphosa announced the start date of vaccinations for all people over 18 and announced that within the next 2 to 3 months an additional 31 million doses of the Pfizer vaccine and the Janssen vaccine will arrive. [150]

On 26 July 2021, 968,760 Doses of the Pfizer vaccine arrived at O.R Tambo International Airport. [54] [57]

On 31 July 2021, 2,830,000 doses of the Pfizer vaccine donated by the USA arrived at O.R Tambo International Airport. 7.6 million vaccine doses had been administered by the end of July, while 12% of the target population had been fully vaccinated.

August 2021

On 13 August 2021, the Department of Health announced that although vaccine supply had stabilised, demand for vaccinations was low. They specifically pointed out a lack of sustained interest from the 35-50 age group and men across the country in general. They further adjusted their goal to have 28 million people vaccinated by the end of December by administering approximately 35 million doses. [151] [152]

On 18 August 2021, Cabinet approved the early start of vaccinations for all over 18, to increase demand. The start date was moved from 1 September to 20 August [22] [150]

On 20 August 2021, the rollout began for all documented persons over 18, with 560 000 registrations in the 18-34 group on the first day. [153]

On 27 August 2021, the Department of Health announced that the US would donate another 2.2 Million Pfizer vaccines. They further stated that low weekend vaccinations were due to lack of health care workers able to work weekends with the hope that as the 3rd wave ends more workers would become available.They also said that they were in the process of procuring AstraZeneca vaccine due to data that it is efficacious against the Delta variant but were unable to find a supplier with stock. They expected stock to become available in September/October. They reiterated that they had not yet ordered CoronaVac as they were still waiting for further clinical data. [61] [154] [155] [156] [157] [158] [159]

On 30 August 2021, the Department of Health released an updated circular recommending all pregnant and lactating women get vaccinated with either of the available vaccines. [160]

By the end of the month, 11.1 million vaccine doses had been administered. 19% of the target population had been fully vaccinated by the end of the month.

September 2021

On 3 September 2021, the health minister stated vaccinations would only open to those under 18 once 70% of the over 18 population was vaccinated. The country had the capacity to vaccinate between 300 000 and 400 000 people a day. The Government was not yet mandating vaccinations but would rather try incentivise through entrance to entertainment, cultural and sporting events. [161] [162] [163] [164]

On 10 September 2021, the health minister announced plans for issuing digital vaccine certificates, which would be printable and would be issued to all people with vaccination data already on the EVDS platform. These certificates would be in line with WHO guidelines to prevent fraud. [165] [166] [167] [168]

On 11 September 2021, SAHPRA announced that the EUA for the Pfizer–BioNTech vaccine was extended to include all people 12 and older, creating opportunity for teenagers and children to be included in the vaccination rollout in the future. [169] [170]

On 15 September 2021, a circular was released to prioritise the Janssen vaccine stock for rural areas, pop up and mobile sites only until the supply stabilises. [171]

On 17 September 2021, the health minister stated that they were currently focussing on vaccinating people 50 years and older but would review the decision to open to under 18s at the end of October. [172] The Draft implementation of the digital vaccine certificates would be submitted to the national coronavirus command council in 2 weeks and would be rolled out once approved. The certificates would not be used for access to essential services but would give vaccinated people access to more activities. The government would not implement vaccine mandates in the public sector but would not interfere with mandates in the private sector and at higher education institutions as long as the mandates are implemented legally. [173] [174] [175] [176] [177]

On 29 September 2021, the health department confirmed that the vaccine certificate would be made available on 5 October. It would be downloadable from a website and could be printed. It would have a QR code to scan to verify authenticity and would link to the person's ID number. [178] [179] [180] [181] [182]

On 30 September 2021, President Ramaphosa stated that 60% of people over 60 and 50% of those between 50 and 59 had received at least one vaccine dose. He further restated the goal of vaccinating 70% of adults by the year end in hope to save up to 20 000 lives. [183]

By the end of the month, 17.8 million vaccine doses had been administered. 38% of the target population had been fully vaccinated by the end of the month.

October 2021

On 5 October 2021, the vaccine certificate system went online in a testing phase with the full release planned for Friday. [184] [185] [186] [187]

On 6 October 2021, the health department confirmed that expiry dates were present on the vaccine certificates due to plans to update the system to increase security and comply with future international standards. There were plans to release a second version at the end of October and a third at the end of November [188] [189] [190]

On 8 October 2021, the vaccine certificates officially launched. However, verifying the authenticity of the certificate by scanning the QR code would only be implemented at the end of October. The certificate could be used for international travel, with the UK already confirming they would accept it from 11 October. The health department confirmed that an announcement about vaccinating people between 12 and 18 would be made before the end of October. [191] [192] [193] [194] [195]

On 15 October 2021, the health department confirmed that vaccinations would open to people 12 to 17 on Wednesday 20 October. They could receive 1 Pfizer dose at any vaccination site and would not require parents' consent. They would not currently get a second dose due to concerns of myocarditis in teenage boys. The Ministerial Adversary Committee also recommended a 2nd Jansen shot for all Sisonke trial participants, pending SAHPRA approval. Doses for this program would be donated by Johnson & Johnson. The health department also confirmed that pilot programs were in place to vaccinate undocumented people at specific vaccination sites and would be slowly expanded. [196] [197] [198] [199] [200] [201]

On 18 October 2021, SAHPRA announced that they would not be authorising the Sputnik V vaccine for emergency use due to concerns about the use of Ad5-vectored vaccines in a population at high risk of HIV infections and the fact that the vaccine had not received Emergency Use Listing by the WHO. The rolling review would, however, remain open for further data to be submitted. [202]

On 19 October 2021, vaccinations opened to people 12 to 17 with 39 109 registrations (0.6% of the age group) on the first day. [203]

By the end of the month, 22.4 million vaccine doses had been administered. 51% of the target population had been fully vaccinated by the end of the month.

Vaccine Trials

On 17 March 2020, the South African Health Products Regulatory Authority announced that it would expedite review of treatments, vaccines and clinical trials. Currently a total of 6 vaccine candidates are under trial in South Africa. [204] [205] [206]

Vaccine Trials
VaccineType (technology)Phase IPhase IIPhase IIIStatus
Johnson & Johnson Viral vector N/AGreen check.svg CompletedGreen check.svg CompletedApproved
Pfizer–BioNTech RNA N/AGreen check.svg CompletedGreen check.svg CompletedApproved
Oxford–AstraZeneca Viral vector Green check.svg CompletedGreen check.svg CompletedN/ASuspended
Novavax Subunit N/AGreen check.svg CompletedIn progressN/A
GRAd-COV2 Viral vector N/AGreen check.svg CompletedIn progressN/A
ImmunityBio Viral vector In progressIn progressDark Red x.svg Not yetN/A

Janssen (Ad26.COV2.S)

Sisonke Logo Sisonke Logo White.png
Sisonke Logo

Both Phase II and Phase III trials were conducted in South Africa beginning late February 2021 and April 2021. [207]

Phase II Trials, enrolled about 800 across Spain, United Kingdom and United States of America and proved to be 64% effective. [208] [209]

Phase III Trials under Sisonke Protocol began early April enrolling 500,000 participants. This trial was completed successfully, it consisted of half a million of South Africa's health workers and Phase I of the vaccine rollout. [210] [211] [207]

In January, Johnson & Johnson, which held trials for its Janssen vaccine in South Africa, reported the level of protection against moderate to severe COVID-19 infection was 72% in the United States, but 57% in South Africa. [212]

Pfizer–BioNTech (BNT162b2)

Both Phase II and Phase III trials were conducted in South Africa beginning late May 2020. Pfizers vaccine appeared to be 100% effective at preventing cases of the South African variant, B.1.351. [213] [214] [215]

On 17 February 2021, Pfizer announced neutralization activity was reduced by two thirds for the 501.V2 variant, while stating no claims about the efficacy of the vaccine in preventing illness for this variant could yet be made. [216] [217] [218]

Oxford–AstraZeneca (AZD1222)

Both Phase I and Phase II were conducted in South Africa. [207] Phase 1 and Phase 2 trials began mid June 2020 consisting of about 2,130 participants. [219] The trial revealed that the vaccine does not have at least 60% efficacy against mild-moderate Covid-19 due to the B.1.351 (501Y.V2) variant. This resulted in the vaccine being suspended and the 1 million doses derived being sold to other Members of the African Union. [220] [221] [222]

On 6 February 2021, The Financial Times reported that provisional trial data from a study undertaken by South Africa's University of the Witwatersrand in conjunction with Oxford University demonstrated reduced efficacy of the Oxford–AstraZeneca COVID-19 vaccine against the 501.V2 variant. The study found that in a sample size of 2,000 the AZD1222 vaccine afforded only "minimal protection" in all but the most severe cases of COVID-19. [90]

On 7 February 2021, the Minister for Health for South Africa suspended the planned deployment of around 1 million doses of the vaccine whilst they examined the data and awaited advice on how to proceed. [223] Ultimately, around March 2021, the roll-out of Oxford–AstraZeneca vaccine in South Africa was cancelled, and the short-dated stock offered to other African countries.

Novavax (NVX-CoV2373)

A Phase II Trial of 4,400 people was conducted from August 2020 to November 2021 in South Africa, that showed that the vaccine was 51% effective, compared to 89% in the US [210] [211] [207]

The vaccine had an efficacy of 51% against infections caused by the South African variant among people who were HIV negative. The vaccine was only 43% effective in the group that included people who were HIV positive. [224]

ReiThera (GRAd-COV2)

Phase II and Phase III trials of the GRAd-COV2 vaccine are being conducted in South Africa. [225] [226]

ImmunityBio (ImmunityBio)

The BioVac Institute, a state-backed South African vaccine company, has a contract with American based ImmunityBio Inc. to manufacture coronavirus vaccines. [227] [228] [229]

ImmunityBio is currently conducting Phase I and Phase II trials. Trials began January 2021 consisting of about only 35 participants in Phase I. [230] [207]

Vaccine Effectiveness

Johnson & Johnson (Ad26.COV2.S)

In January, Johnson & Johnson, which held trials for its Janssen vaccine in South Africa, reported the level of protection against moderate to severe COVID-19 infection was 72% in the United States, but 57% in South Africa. [212]

After Phase III trials in South Africa completed, Johnson and Johnson received Section 21 approval from SAHPRA on 31 March 2021.

In a manufacturing deal, Johnson and Johnson began to manufacture 220 million vaccines at the Aspen Pharmacare manufacturing facility in Port Elizabeth, Eastern Cape. They plan to distribute the vaccine to other African countries with 30 million to go to South Africa. [231] [92] [91]

Oxford–AstraZeneca (AZD1222)

On 6 February 2021, The Financial Times reported that provisional trial data from a study undertaken by South Africa's University of the Witwatersrand in conjunction with Oxford University demonstrated reduced efficacy of the Oxford–AstraZeneca COVID-19 vaccine against the 501.V2 variant. The study found that in a sample size of 2,000 the AZD1222 vaccine afforded only "minimal protection" in all but the most severe cases of COVID-19. [90]

On 7 February 2021, the government suspended the planned deployment of around 1 million doses of the vaccine whilst they examined the data and awaited advice on how to proceed. [223] The South African government subsequently cancelled the use of the vaccine, selling its supply to other African countries, and switched its vaccination program to use the Janssen COVID-19 vaccine. [232] [233] [234] [lower-alpha 2]

On 27 August 2021, the government announced that they were in the process of procuring the Oxford–AstraZeneca COVID-19 vaccine due to data showing good protection against the Delta variant but were only expecting stock to become available late September/early October. [155] [156]

Sputnik V (Gam-COVID-Vac)

The South African Health Products Regulatory Authority (SAHPRA) has confirmed that it has received documentation for the vaccine developed by the Gamaleya Institute in Russia. [235]

Sputnik V is one of three Covid vaccines worldwide with an efficacy higher than 90% in symptomatic cases. They are still in the process of testing its effectiveness against the 501Y.V2 variant of the virus. [236]

Pfizer–BioNTech (BNT162b2)

On 17 February 2021, Pfizer announced neutralization activity[ clarification needed ] was reduced by two thirds for the 501.V2 variant, while stating no claims about the efficacy of the vaccine in preventing illness for this variant could yet be made. [237]

On 16 March 2021, The South African Health Products Regulatory Authority (SAHPRA) approved the Pfizer-BioNTech vaccine for section 21 Emergency Use Authorisation. [82]

A trial ending in March 2021 of the Pfizer-BioNTech's COVID-19 vaccine appeared to be 100% effective at preventing cases of the South African 501Y.V2 variant. The trial consisted of 800 people, with a total of 9 cases, all in the placebo group. [238] [239]

Pfizer-BioNTech vaccine Covid19 vaccine biontech pfizer 3.jpg
Pfizer–BioNTech vaccine

Moderna (mRNA-1273)

In February, Moderna reported that the current vaccine produced only one-sixth of the antibodies in response to the South African variant compared with the original virus. They have launched a trial of a new vaccine to tackle the South African 501.V2 variant. [240]

Sinopharm (BBIBP-CorV)

Other African countries have begun the roll out of the Sinopharm vaccine, including Morocco, Egypt, The Seychelles and Zimbabwe. [241] So far, it has proven resistant[ clarification needed ] to the 501Y.V2 variant, as seen in Zimbabwe. [242]

CoronaVac (Sinovac)

CoronaVac is yet to be approved for use by the South African Health Products Regulatory Authority (SAHPRA). [243]

On 3 July 2021, the vaccine was approved under section 21, EUA. Sinovac will supply South Africa with 5 million doses of the vaccine, beginning in July 2021. [244] [245]

Covaxin (BBV152)

Bharat Biotech, producers of the Covaxin vaccine, have said that they can modify the vaccine against coronavirus South African variant within 15 days. [246]

CoviVac (КовиВак)

The CoviVac vaccine Information has not been delivered to the South African government yet. [247]

EpiVacCorona (EpiVacCorona)

The EpiVacCorona vaccine Information has not been delivered to the South African government yet. [248]

RBD-Dimer (ZF2001)

The RBD-Dimer vaccine Information is in the process of being delivered to the South African Government.

Novavax (V2373)

A study on the NVX-CoV2373 Novavax vaccine showed 60% efficacy (for HIV-negative participants) in South Africa, compared to 90% efficacy in Britain. [249] [250]

ImmunityBio (ImmunityBio)

The BioVac Institute, a state-backed South African vaccine company, plans to use a deal it won to manufacture coronavirus vaccines. The contract with American based ImmunityBio Inc is currently conducting phase 1 vaccine trials with their hAd5 vaccine in the United States and South Africa. [227]

ImmunityBio and BioVac plan to distribute the vaccines throughout South African and Africa. [228] [229]

Vaccine Exports

South Africa is the first country in Africa to locally manufacture any covid vaccine. [40] [41] The vaccines are to be reserved for purchased exclusively to Africa. South Africa is currently manufacturing 220 000 million doses of the Johnson & Johnson vaccine in Port Elizabeth. [251] Pfizer-BioNTech production is expected to begin in Cape Town end of 2021. [146] [148] If the ImmunityBio vaccine makes it through the trails, manufacturing will commence locally. [228]

Export Consignments

Johnson & Johnson Export
CountryDosesDateReference
South Africa1.5 Million26 July 2021 [42] [40]
Europe32 MillionAugust 2021 [252] [253] [254]
TBA17 MillionTBA (August–September) [141]
Pfizer-BioNTech Export
CountryDosesDateReference
TBA100 MillionTBA (2021) [255] [148]

Timeline

On 11 July 2021, President Cyril Ramaphosa addressed the nation and announced that South Africa will be delivering 17 million doses of the Johnson and Johnson vaccine to members of the African Union over the next 3 months. [141]

On 26 July 2021, the first batch of 1.5 million doses of the Johnson & Johnson vaccine were cleared for release at Aspens Facility in Port Elizabeth. [252] [41] The vaccines were transported from Port Elizabeth Airport to O. R. Tambo International Airport in Johannesburg via Star Air Cargo at 21:39 (SAST). [253] [251] The vaccines are then expected to be transported to a facility in Midrand for testing and distribution in the days to come. [40]

On 16 August 2021, the New York Times released a report stating that around 32 million vaccines finished at the Aspens Facility had been exported to countries in Europe. They further claimed that in the agreement to order doses, the South African Government had waived its right to ban exports and had paid more than the European commission per dose. [254] [256]

On 17 August 2021, the Health Justice Initiative filed a request under South Africa's Promotion of Access to Information Act to get access to the contracts between Johnson & Johnson and the South African government, prompted by the New York Times report. [257] [258]

On 2 September 2021, the AU coronavirus envoy stated that vaccine shipments from Aspens Facility to Europe had been suspended and 20 million doses already sent to Europe would be returned for distribution across Africa. [259] [260]

Statistics

National

The most up to date vaccination statistics can be found on SACoronavirus site.

Cumulative vaccinations in South Africa

Graph of cumulative doses administered across the country

  Fully vaccinated (All doses)  Partially vaccinated (1st dose only)

Provincial

Daily Covid-19 vaccinations by province as of 7 August 2021 Daily Covid-19 vaccination in South Africa.svg
Daily Covid-19 vaccinations by province as of 7 August 2021
ProvinceTotal Doses
Eastern Cape1,107,038
Free State465,412
Gauteng2,118,874
KwaZulu-Natal1,613,565
Limpopo941,632
Mpumalanga409,232
North West443,191
Northern Cape163,629
Western Cape1,325,891

Progress By Province

Progress Table

DateDoses AdministeredVaccinated (1 Dose)Fully VaccinatedRef
17 February 2021000 [261]
18 February 20212,26002,260 [262]
19 February 20216,52406,524 [263]
20 February 202110,414010,414 [264]
21 February 202115,388015,388 [265]
22 February 202123,059023,059 [266]
23 February 202132,315032,315 [267]
24 February 202141,809041,809 [268]
25 February 202152,647052,647 [269]
26 February 202163,648063,648 [270]
27 February 202167,303067,303 [271]
28 February 202170,527070,527 [272]
1 March 202173,047073,047 [273]
2 March 202176,037076,037 [274]
3 March 202183,570083,570 [275]
4 March 202192,029092,029 [276]
5 March 2021100,1080100,108 [277]
6 March 2021101,5730101,573 [278]
7 March 2021101,8410101,841 [279]
8 March 2021107,0540107,054 [280]
9 March 2021118,2470118,247 [281]
10 March 2021128,8870128,887 [282]
11 March 2021138,0140138,014 [283]
12 March 2021145,2150145,215 [284]
13 March 2021145,5440145,544 [285]
14 March 2021145,5440145,544 [286]
15 March 2021147,7530147,753 [287]
16 March 2021157,2860157,286 [288]
17 March 2021168,4130168,413 [289]
18 March 2021177,2750177,275 [290]
19 March 2021182,9830182,983 [291]
20 March 2021182,9830182,983 [292]
21 March 2021182,9830182,983 [293]
22 March 2021182,9830182,983 [294]
23 March 2021194,2570194,257 [295]
24 March 2021207,8080207,808 [296]
25 March 2021220,1290220,129 [297]
26 March 2021231,0020231,002 [298]
27 March 2021231,6050231,605 [299]
28 March 2021239,6650239,665 [300]
29 March 2021251,7070251,707 [301]
30 March 2021263,8780263,878 [302]
31 March 2021269,1020269,102 [303]
1 April 2021269,1020269,102 [304]
2 April 2021269,1020269,102 [305]
3 April 2021269,1020269,102 [306]
4 April 2021269,1020269,102 [307]
5 April 2021269,1020269,102 [308]
6 April 2021272,4380272,438 [309]
7 April 2021278,9090278,909 [310]
8 April 2021283,6290283,629 [311]
9 April 2021288,3680288,368 [312]
10 April 2021288,4060288,406 [313]
11 April 2021288,4060288,406 [314]
12 April 2021289,7870289,787 [315]
13 April 2021292,6230292,623 [316]
14 April 2021292,6230292,623 [317]
15 April 2021292,6230292,623 [318]
16 April 2021292,6230292,623 [319]
17 April 2021292,6230292,623 [320]
18 April 2021292,6230292,623 [321]
19 April 2021292,6230292,623 [322]
20 April 2021292,6230292,623 [323]
21 April 2021292,6230292,623 [324]
22 April 2021292,6230292,623 [325]
23 April 2021292,6230292,623 [326]
24 April 2021292,6230292,623 [327]
25 April 2021292,6230292,623 [328]
26 April 2021298,1530298,153 [329]
27 April 2021298,1530298,153 [330]
28 April 2021298,1530298,153 [331]
29 April 2021307,5910307,591 [332]
30 April 2021317,6560317,656 [333]
1 May 2021318,6700318,670 [334]
2 May 2021318,6700318,670 [335]
3 May 2021329,0980329,098 [336]
4 May 2021339,6550339,655 [337]
5 May 2021353,1810353,181 [338]
6 May 2021366,1010366,101 [339]
7 May 2021381,1710381,171 [340]
8 May 2021382,4800382,480 [341]
9 May 2021382,4800382,480 [342]
10 May 2021395,2300395,230 [343]
11 May 2021414,3720414,372 [344]
12 May 2021430,7300430,730 [345]
13 May 2021455,1690455,169 [346]
14 May 2021474,3180474,318 [347]
15 May 2021478,4520478,452 [348]
16 May 2021478,7330478,733 [349]
17 May 2021478,7330478,733 [350]
18 May 2021519,13939,371479,768 [351]
19 May 2021558,17077,505480,665 [352]
20 May 2021597,406116,741480,665 [353]
21 May 2021642,382161,717480,665 [354]
22 May 2021647,983167,318480,665 [355]
23 May 2021651,628171,860479,768 [356]
24 May 2021700,904221,136479,768 [357]
25 May 2021761,903282,135479,768 [358]
26 May 2021828,204348,436479,768 [359]
27 May 2021898,955418,187479,768 [360]
28 May 2021963,876484,108479,768 [361]
29 May 2021968,319488,551479,768 [362]
30 May 2021970,448490,680479,768 [363]
31 May 20211,045,104565,336479,768 [364]
1 June 20211,117,569637,801479,768 [365]
2 June 20211,193,352713,584479,768 [366]
3 June 20211,266,893787,125479,768 [367]
4 June 20211,336,547856,779479,768 [368]
5 June 20211,343,433863,665479,768 [369]
6 June 20211,350,245870,477479,768 [370]
7 June 20211,433,730953,962479,768 [371]
8 June 20211,525,2711,045,503479,768 [372]
9 June 20211,619,0111,139,243479768 [373]
10 June 20211,690,0261,210,258479768 [374]
11 June 20211,767,4151,287,647479768 [375]
12 June 20211,773,4171,293,649479768 [376]
13 June 20211,777,2881,297,520479768 [377]
14 June 20211,871,9871,392,219479768 [378]
15 June 20211,965,8121,486,044479,768 [379]
16 June 20211,974,0991,494,331479,768 [380]
17 June 20212,069,3461,589,578479,768 [381]
18 June 20212,137,0711,657,303479,768 [382]
19 June 20212,141,6241,661,856479,768 [383]
20 June 20212,144,2041,664,436479,768 [384]
21 June 20212,229,2421,749,474479,768 [385]
22 June 20212,312,8731,833,105479,768 [386]
23 June 20212,442,262TBATBA [386]
24 June 20212,558,490TBATBA [386]
25 June 20212,666,244TBATBA [386]
26 June 20212,683,788TBATBA [386]
27 June 20212,684,999TBATBA [386]
28 June 20212,787,996TBATBA [386]
29 June 20212,900,666TBATBA [386]
30 June 20213,026,636TBATBA [386]
1 July 20213,155,717TBATBA [386]
2 July 20213,296,205TBATBA [387]
3 July 20213,318,900TBATBA [388]
4 July 20213,325,307TBATBA [388]
5 July 20213,467,560TBATBA [388]
6 July 20213,643,387TBATBA [388]
7 July 20213,828,063TBATBA [388]
8 July 20214,017,4422,385,0611,253,978 [388]
9 July 20214,203,2932,858,6031,344,690 [389]
10 July 20214,225,0212,872,8081,352,213 [390]
11 July 20214,236,7182,880,9751,355,743 [391]
12 July 20214,408,0272,984,0981,406,793 [392]
13 July 20214,544,7503,079,8121,462,737 [393]
14 July 20214,688,7793,162,9041,525,875 [393]
15 July 20214,869,7593,265,4991,604,260 [394]
16 July 20215,046,2673,372,1151,674,152 [395]
17 July 20215,079,2153,394,8991,683,763 [396]
18 July 20215,095,0133,406,4991,688,514 [396]
19 July 20215,328,1103,541,1711,786,939 [397]
20 July 20215,558,3783,664,7781,893,600 [398]
21 July 20215,831,3893,802,9922,028,397 [399]
22 July 20216,085,1083,930,1862,154,922 [400]
23 July 20216,308,2014,033,9342,274,267 [401]
24 July 20216,364,936TBATBA [402]
25 July 20216,384,3824,072,8232,311,559 [402]
26 July 20216,613,7044,176,5372,437,167 [403]
27 July 20216,854,6674,274,6662,580,001 [404]
28 July 20217,065,4324,374,3542,691,078 [405]
29 July 20217,297,9124,461,9822,835,930 [406]
30 July 20217,504,3734,549,9442,954,429 [407]
31 July 20217,544,5394,570,1352,974,404 [408]
1 August 20217,567,7574,584,8052,982,952 [408]
2 August 20217,769,7994,677,3983,092,401 [409]
3 August 20217,981,8224,768,8483,212,974 [410]
4 August 20218,182,3804,854,4303,327,950 [411]
5 August 20218,377,6064,930,2263,447,380 [412]
6 August 20218,546,4285,002,2073,544,221 [413]
7 August 20218,588,4645,018,7113,569,753 [414]
8 August 20218,602,1245,025,4263,576,698 [415]
9 August 20218,621,9325,030,4373,591,495 [416]
10 August 20218,811,6085,092,1003,719,508 [417]
11 August 20219,002,0525,162,4833,839,569 [418]
12 August 20219,185,7565,227,5253,958,231 [419]
13 August 20219,339,7555,285,4884,054,267 [420]

Daily vaccinations chart of South Africa

2021 Civil Unrest

During the 2021 South African unrest, the vaccine rollout encountered a slowdown as businesses and vaccine sites were shut down due to protests and looting in Gauteng and Kwazulu-Natal. [142] [143] [144]

It is estimated that 47 500 vaccine doses and 120 private pharmacies were destroyed during the unrest. [421]

Distribution

Vaccines administered per pharmaceutical company as of 27 Jul 2021 (9 339 755)

  Johnson & Johnson (2 067 035) (22.13%)
  Pfizer–BioNTech (7 272 720) (77.87%)
  Oxford–AstraZeneca (0) (0%)

Doses administration by vaccine type in South Africa

Graph of cumulative doses administered by vaccine type as of 15 June 2021

   Johnson & Johnson   Pfizer-BioNTech   Oxford-AstraZeneca [lower-alpha 3]    CoronaVac

Vaccines distribution

As of 13 August 2021
1,000,000
2,000,000
3,000,000
4,000,000
5,000,000
6,000,000
7,000,000
8,000,000
  •   Johnson & Johnson
  •   Pfizer–BioNTech
  •   Oxford-AstraZeneca
  •   CoronaVac

Vaccination sites

The COVID-19 Vaccine can be obtained at 1397 [1] different locations nationwide, as of 28 August. Any person qualified for a vaccine will be allocated to the most appropriate site, regardless if it is private or public or if they are insured or not. [140] Vaccination sites are expected to increase to 3,338 locations, as Phase II and Phase III progress ramps up. [422] So far it is planned that all Clicks, Dis-Chem, and other pharmacies and hospitals nationwide be used to distribute vaccines. [423] [424]

The Chris Hani Baragwanath Hospital, Soweto.jpg
Charlotte.Maxeke. Joburg.Hospital.JPG
Kbh.jpg
Tygerberg from air.jpg
Vaccination Sites in South Africa

Planned vaccination sites

ProvinceSmallMediumLargeX-LargeTotal
Eastern Cape96611158
Free State5227180
Gauteng555164141734
Kwa-Zulu Natal778584840
Limpopo55991569
Mpumalanga9111102
North West4726174
Northern Cape1678175
Western Cape5128491606
Total28574483123,338

Active Sites

A list of active sites can be found on the SACoronavirus site.

See also

Notes

  1. as of 12 August 2021
  2. South Africa's Oxford-AstraZeneca vaccine was sold to African Union members and the additional 500,000 Doses were canceled
  3. The Oxford-AstraZeneca vaccine is current suspended

Related Research Articles

The Electronic Vaccination Data System or EVDS is the South African Self vaccination portal. Registration is currently available for everyone over the age of 18, with registration to open for those aged 12 to 18 to open on the 20th of October 2021.

CoronaVac Vaccine against COVID-19

CoronaVac, also known as the Sinovac COVID-19 vaccine, is an inactivated virus COVID-19 vaccine developed by the Chinese company Sinovac Biotech. It was Phase III clinical trialled in Brazil, Chile, Indonesia, the Philippines, and Turkey and relies on traditional technology similar to other inactivated-virus COVID-19 vaccines, such as BBIBP-CorV, another Chinese vaccine, and Covaxin, an Indian vaccine. CoronaVac does not need to be frozen and both the final product and the raw material for formulating CoronaVac can be transported refrigerated at 2–8 °C (36–46 °F), temperatures at which flu vaccines are kept.

COVID-19 Vaccines Global Access, abbreviated as COVAX, is a worldwide initiative aimed at equitable access to COVID-19 vaccines directed by Gavi, the Vaccine Alliance, the Coalition for Epidemic Preparedness Innovations (CEPI), and the World Health Organization (WHO). It is one of the three pillars of the Access to COVID-19 Tools Accelerator, an initiative begun in April 2020 by the WHO, the European Commission, and the government of France as a response to the COVID-19 pandemic. COVAX coordinates international resources to enable low-to-middle-income countries equitable access to COVID-19 tests, therapies, and vaccines. UNICEF is the key delivery partner, leveraging its experience as the largest single vaccine buyer in the world and working on the procurement of COVID-19 vaccine doses, as well logistics, country readiness and in-country delivery.

Sinopharm BIBP COVID-19 vaccine Vaccine against COVID-19

The Sinopharm BIBP COVID-19 vaccine, also known as BBIBP-CorV, the Sinopharm COVID-19 vaccine, or BIBP vaccine, is one of two inactivated virus COVID-19 vaccines developed by Sinopharm's Beijing Institute of Biological Products. It completed Phase III trials in Argentina, Bahrain, Egypt, Morocco, Pakistan, Peru, and the United Arab Emirates (UAE) with over 60,000 participants. BBIBP-CorV shares similar technology with CoronaVac and Covaxin, other inactivated virus vaccines for COVID-19. Its product name is SARS-CoV-2 Vaccine, not to be confused with the similar product name of CoronaVac.

SARS-CoV-2 Beta variant Variant of the SARS-CoV-2 virus

Beta variant, also known as lineage B.1.351, is a variant of SARS-CoV-2, the virus that causes COVID-19. One of several SARS-CoV-2 variants believed to be of particular importance, it was first detected in the Nelson Mandela Bay metropolitan area of the Eastern Cape province of South Africa in October 2020, which was reported by the country's health department on 18 December 2020. Phylogeographic analysis suggests this variant emerged in the Nelson Mandela Bay area in July or August 2020.

COVID-19 vaccination in Switzerland Plan to immunize against COVID-19

COVID-19 vaccination in Switzerland is an ongoing immunization campaign against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), in response to the ongoing pandemic in the country.

COVID-19 vaccination in Israel

Israel's COVID-19 vaccination programme, officially named "Give a Shoulder", began on 19 December 2020, and has been praised for its speed, having given twenty percent of the Israeli population the first dose of the vaccines' two dose regimen in the span of three weeks.

COVID-19 vaccination in Australia Ongoing COVID-19 vaccine program in Australia

The general COVID-19 vaccination in Australia program began on 22 February 2021 in response to the COVID-19 pandemic, and will continue with the goal of vaccinating all willing Australians before 2022. Front-line workers and aged care staff and residents will be the first Australians to be inoculated, before a gradual phased release to less-vulnerable and lower-risk population groups throughout 2021. The Therapeutic Goods Administration (TGA) approved four vaccines for Australian use in 2021: the Pfizer–BioNTech vaccine on 25 January, the Oxford–AstraZeneca vaccine on 16 February, Janssen vaccine on 25 June and the Moderna vaccine on 9 August. Although approved for use, the Janssen vaccine is not included in the Australian vaccination program.

COVID-19 vaccination in Malaysia

The National COVID-19 Immunisation Programme, abbreviated as NIP or PICK, is a national vaccination campaign that is currently being implemented by the Malaysian government as an approach in curbing the spread of coronavirus disease 2019 (COVID-19) and to end the COVID-19 pandemic in Malaysia by successfully achieving the highest immunisation rate among its citizens and non-citizens that are residing in Malaysia. It is the largest immunisation programme implemented in the history of the country and it is being administrated by The Special Committee For Ensuring Access To COVID-19 Vaccine Supply (JKJAV) since early 2021.

COVID-19 vaccination in Angola is an ongoing immunisation campaign against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), in response to the ongoing pandemic in the country.

COVID-19 vaccination in Botswana is an ongoing immunisation campaign against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), in response to the ongoing pandemic in the country.

COVID-19 vaccination in New Zealand Ongoing COVID-19 vaccine programme in New Zealand

COVID-19 vaccination in New Zealand began on 20 February 2021, and will continue throughout the year with the goal of vaccinating all willing New Zealanders aged 12+. As of 1 September, anyone in New Zealand is eligible to be vaccinated.

COVID-19 vaccination in Africa Immunisation programme against COVID-19 in Africa

COVID-19 vaccination programs have begun in many countries and territories in Africa. As of 5 July 2021, vaccination campaigns had started in 51 African countries with 36.5 million people receiving at least one dose.

COVID-19 vaccination in Bhutan

Bhutan has promised a free COVID-19 vaccination to all of its citizens, both inside and outside the country. It started mass vaccinations on 27 March 2021.

COVID-19 vaccination in Indonesia

The COVID-19 vaccination in Indonesia is an ongoing mass immunization in response to the COVID-19 pandemic in Indonesia. On 13 January 2021, the program commenced when President Joko Widodo was vaccinated at the presidential palace. In terms of total doses given, Indonesia ranks fifth in the world and second in Asia.

COVID-19 vaccination in Singapore Plan to immunize against COVID-19

COVID-19 vaccination in Singapore is an ongoing immunisation campaign against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), in response to the ongoing pandemic in the country.

COVID-19 vaccination in Brazil

The COVID-19 vaccination campaign in Brazil is an ongoing mass immunization campaign for the COVID-19 pandemic in Brazil. It started on January 17, 2021, when the country had 210 thousand deaths.

COVID-19 vaccination in Sri Lanka Plan to immunize against COVID-19

COVID-19 vaccination in Sri Lanka is an ongoing immunisation campaign against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, in response to the ongoing pandemic in the country. As of late July, Sinopharm's BBIBP-CorV accounted for 78% of the total 13.8 million vaccines obtained by Sri Lanka to date. The United States donated over 1.5 million Moderna COVID-19 vaccine through COVAX.

COVID-19 vaccination in Ukraine Plan to immunize against COVID-19

The COVID-19 vaccination campaign in Ukraine is an ongoing mass immunization campaign for the COVID-19 pandemic in Ukraine.

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  2. "New Covid-19 vaccine sites confirmed in Cape Town and Joburg – but Durban lags behind". BusinessInsider. Retrieved 17 May 2021.
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  4. Staff Writer. "South Africa sets aside extra R4 billion for Covid-19 vaccines and grants" . Retrieved 4 May 2021.
  5. "Budget 2021: R10 billion allocated for Covid-19 vaccines". www.iol.co.za. Retrieved 5 March 2021.
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