Stemirna COVID-19 vaccine

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Stemirna COVID-19 vaccine
Vaccine description
Target SARS-CoV-2
Vaccine type mRNA
Clinical data
Other namesSW 0123
Routes of
administration 		Intramuscular
Identifiers
CAS Number

Stemirna COVID-19 vaccine is a COVID-19 vaccine candidate developed by Stemirna Therapeutics. [2] [3] The Stemirna COVID-19 vaccine is labeled as a mRNA vaccine which means it causes the body to make a protein specific to the vaccine which triggers a immune response from the body. [4] Stemirna first started the production of vaccines in result of the COVID-19 pandemic, therefore the first vaccine the began producing was a COVID-19 vaccine. [5]

Contents

Research

Testing on mice and other non human primates, the vaccine showed results that would lead the body to produce antibodies that would stop the spread and limit the coronavirus therefore the vaccine seemed very promising for human trials. [4] Stemirna explains that the research in Nanotechnology has been a big help into researching and create possible vaccines for the COVID-19 virus. [6]

History

Stemirna Therapeutics raised a total of 1.2 Billion RMB (Renminbi) which translates to a little less than 200 million US Dollars for the start of their production and testing trials. [5] Li Hangwen, a co-founder of the company, stated they were confident in the vaccine's efficacy and safety based on ongoing Phase 1 and Phase 2 trial data conducted in Laos. [7] Stemirna Therapeutics first began their clinical trials in Brazil as part of its Phase 3 testing. [7] Li Hangwen, who is the chief executive of the company said that they were going to be able to produce 400 million doses of the vaccine each year. [7] The stemirna Vaccine uses nanotechnology which has helped to quickly create diagnostic tools, vaccines, and antiviral treatments for SARS-CoV-2. [6]


References

  1. ↑ World Intellectual Property Organization. (2022). COVID-19-related vaccines and therapeutics: Preliminary insights on related patenting activity during the pandemic (PDF). Geneva: World Intellectual Property Organization. doi:10.34667/tind.45030. ISBN   978-92-805-3359-0.
  2. ↑ "Randomized, double-blind, placebo-controlled phase I clinical trial to evaluate the safety and immunogenicity of mRNACOVID-19 vaccine in healthy susceptible populations aged 18 years and older people". Chinese Clinical Trial Registry (ChiCTR). Archived from the original on 15 May 2021. Retrieved 15 May 2021.
  3. ↑ Clinical trial number NCT05144139 for "A Phase I/II Clinical Trial in Healthy People Aged 18 Years and Above" at ClinicalTrials.gov
  4. 1 2 Yang R, Deng Y, Huang B, Huang L, Lin A, Li Y, et al. (31 May 2021). "A core-shell structured COVID-19 mRNA vaccine with favorable biodistribution pattern and promising immunity". Signal Transduction and Targeted Therapy. 6 (1): 213. doi:10.1038/s41392-021-00634-z. ISSN   2059-3635. PMC   8165147 . PMID   34059617.
  5. 1 2 Taylor NP (4 June 2021). "China's Stemirna raises $188M to fund mRNA COVID-19 vaccine". www.fiercebiotech.com. Retrieved 28 April 2025.
  6. 1 2 Xu C, Lei C, Hosseinpour S, Ivanovski S, Walsh LJ, Khademhosseini A (29 September 2022). "Nanotechnology for the management of COVID-19 during the pandemic and in the post-pandemic era". National Science Review. 9 (10): nwac124. doi:10.1093/nsr/nwac124. ISSN   2095-5138. PMC   9522393 . PMID   36196115.
  7. 1 2 3 Knowlton K (January 1998). "Retrieved icon, 1998". ACM SIGGRAPH 98 Electronic art and animation catalog. New York, NY, USA: ACM. p. 80. doi:10.1145/281388.281648. ISBN   1-58113-045-7.


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