Trehalose 6-phosphate phosphorylase

Last updated
trehalose 6-phosphate phosphorylase
Identifiers
EC no. 2.4.1.216
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a trehalose 6-phosphate phosphorylase (EC 2.4.1.216) is an enzyme that catalyzes the chemical reaction

alpha,alpha-trehalose 6-phosphate + phosphate glucose 6-phosphate + beta-D-glucose 1-phosphate

The two substrates of this enzyme are alpha,alpha'-trehalose 6-phosphate and phosphate. Its two products are glucose 6-phosphate and beta-D-glucose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is alpha,alpha-trehalose 6-phosphate:phosphate beta-D-glucosyltransferase. This enzyme is also called trehalose 6-phosphate:phosphate beta-D-glucosyltransferase.

Related Research Articles

<span class="mw-page-title-main">Glycogen debranching enzyme</span> Mammalian protein found in Homo sapiens

A debranching enzyme is a molecule that helps facilitate the breakdown of glycogen, which serves as a store of glucose in the body, through glucosyltransferase and glucosidase activity. Together with phosphorylases, debranching enzymes mobilize glucose reserves from glycogen deposits in the muscles and liver. This constitutes a major source of energy reserves in most organisms. Glycogen breakdown is highly regulated in the body, especially in the liver, by various hormones including insulin and glucagon, to maintain a homeostatic balance of blood-glucose levels. When glycogen breakdown is compromised by mutations in the glycogen debranching enzyme, metabolic diseases such as Glycogen storage disease type III can result.

<span class="mw-page-title-main">Myophosphorylase</span> Muscle enzyme involved in glycogen breakdown

Myophosphorylase or glycogen phosphorylase, muscle associated (PYGM) is the muscle isoform of the enzyme glycogen phosphorylase and is encoded by the PYGM gene. This enzyme helps break down glycogen into glucose-1-phosphate, so it can be used within the muscle cell. Mutations in this gene are associated with McArdle disease, a glycogen storage disease of muscle.

In enzymology, a 1,3-beta-D-glucan phosphorylase is an enzyme that catalyzes the chemical reaction

In enzymology, a 1,3-beta-oligoglucan phosphorylase is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha,alpha-trehalose-phosphate synthase (GDP-forming) is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha,alpha-trehalose-phosphate synthase (UDP-forming) is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha,alpha-trehalose phosphorylase is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha,alpha-trehalose phosphorylase (configuration-retaining) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Cellobiose phosphorylase</span>

In enzymology, a cellobiose phosphorylase is an enzyme that catalyzes the chemical reaction

In enzymology, a cellodextrin phosphorylase is an enzyme that catalyzes the chemical reaction

In enzymology, a dolichyl-phosphate beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a kojibiose phosphorylase is an enzyme that catalyzes the chemical reaction

In enzymology, a laminaribiose phosphorylase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Maltose phosphorylase</span>

In enzymology, a maltose phosphorylase is an enzyme that catalyzes the chemical reaction

Alpha,alpha-trehalose synthase is an enzyme with systematic name ADP-glucose:D-glucose 1-alpha-D-glucosyltransferase. This enzyme catalyses the following chemical reaction

Beta-D-galactosyl-(1->4)-L-rhamnose phosphorylase is an enzyme with systematic name beta-D-galactosyl-(1->4)-L-rhamnose:phosphate 1-alpha-D-galactosyltransferase. This enzyme catalyses the following chemical reaction

<span class="mw-page-title-main">ALG8 (enzyme class)</span>

Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase is an enzyme with systematic name dolichyl beta-D-glucosyl phosphate:D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha- -D-Man-alpha- - -D-Man-alpha- )-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase.

Nigerose phosphorylase is an enzyme with systematic name 3-O-alpha-D-glucopyranosyl-D-glucopyranose:phosphate beta-D-glucosyltransferase. This enzyme catalyses the following chemical reaction

4-O-beta-D-mannosyl-D-glucose phosphorylase is an enzyme with systematic name 4-O-beta-D-mannopyranosyl-D-glucopyranose:phosphate alpha-D-mannosyltransferase. This enzyme catalyses the following chemical reaction

3-O-alpha-D-glucosyl-L-rhamnose phosphorylase is an enzyme with systematic name 3-O-alpha-D-glucopyranosyl-L-rhamnopyranose:phosphate beta-D-glucosyltransferase. This enzyme catalyses the following chemical reaction

References